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Cba-WM02.98 PRP8 Intein
Intein Name Cba-WM02.98 PRP8
Prototype Allele Cne-AD PRP8
Extein Name PRP8, pre-mRNA splicing factor
Intein Class Theoretical
Organism Name Cryptococcus bacillisporus strain WM02.98 (aka Cryptococcus neoformans gattii)
Organism Description Yeast, human pathogen, taxon:37769
Domain of Life Eucarya
Endonuclease Activity
Endo Motif None
Location in Extein A?
Insert Site Comments PRP8-a, same as A1578 in Sce PRP8
Intein Size (aa) 170
Intein N-terminal TWEGLFWEKA/C
Intein C-terminal HN/SGFEESMKNK
Accession No. AAR00331.1 in NCBI/protein
Intein aa Sequence >gi|37695593|gb|AAR00331.1|CbaPRP8_WM02.98| Cba-WM02.98 PRP8 intein (including -1 and +1 extein residues)
ACLQNGTRLLRADGSEILVEDVQEGDQLLGPDGTSRTASKIVRGEERLYRIKADELEDLVCTHNHILSL
YKKRSGSEQDPSPSTDLSSTDSYERVDVTVDDFVRLPQQEQQKYRLFRSTGFKRADQPSTSSLATLLHI
MSIQLEEKPTKWSGFVVVKDSLYLRHDYLVLHNS
Block A CLQNGTRLLRADG 13
Block B LEDLVCTHNHILSL 68
Block C None
Block D None
Block E None
Block H None
Block F PTKWSGFVVDKDSLYL 161
Block G DYLVLHNS 171
Initially Contributed by Margi Butler
Contributor's Address Department of Biochemistry
University of Otago
PO Box 56
Dunedin
New Zealand/Aotearoa
Contributor's Phone No.
Contributor's FAX No.
Contributor's Email address margi.butler@stonebow.otago.ac.nz
Independently Found By
Comments The organism is also called Cryptococcus neoformans var gattii or Cryptococcus gattii.
Cryptococcus bacillisporus strain CBS8273 (AAX38546 in NCBI/protein) and Cryptococcus bacillisporus strain WM728 (AAX38550 in NCBI/protein) also have PRP8 inteins.
This gene also contains an intron.
Date Submitted 04/27/2003
References Butler 2005

Last database update: 11/05/10

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