InBase Reference: Perler, F. B. (2002). InBase, the Intein Database. Nucleic Acids Res. 30, 383-384.
Splicing Motifs
The entire intein sequence is present in the individual intein files.
N- and C- terminal intein motifs (Blocks A, N2, B, N4, F, and G in the figure above) are involved in protein splicing and not endonuclease activity.
The position in the intein of the last amino acid in each block is listed to the right of the block.
An individual or amino acid group designation (see The Consensus Key below) in the consensus line indicates that the amino acid (upper case letter) or group (lower case letter) is present in a majority of the first 38 inteins sequenced, excluding the highly similar allelic inteins Perler 1997. Dots in the consensus motifs indicate the position of non-conserved amino acids. An asterisk (*) indicates a space added to better align the C-terminal end of Block F and a slash (/) indicates one or more residues were deleted from the block at the position of the slash to better align the C-terminal end of Block F.
Residues in red represent deviations from the conserved residues normally found in those positions in the block.
Intein Block A Block B Block F Block G
Consensus Ch..Dp.hhh..G G..h.hT..H.hhh rVYDLpV**a..HNFh NGhhhHNp |
Eucarya |
Intein Block A Block B Block F Block G
APMV Pol SVTGDTPIITRHQ 13 TGCIDVTEDHSLLD 99 YVYDLET**ESGSFHA 342 GEMIVKNT 352
Abr PRP8 CLAKGTRLLRYDG 13 IEDLVVTPNHILVL 69 TTEWAGFRVDKDQLYL 156 DYLVLHNS 166
Aca-G186AR PRP8 CLAKGTQLLRYDG 13 KEDLVVTPNHILVL 69 MTEWAGFRVDKDQLYL 525 DFLVLHNS 535
Aca-H143 PRP8 CLAKGTQLLRYDG 13 KEDLVVTPNHILVL 69 MTEWAGFRVDKDQLYL 501 DFLVLHNS 511
Aca-JER2004 PRP8 CLAKGTQLLRYDG 13 KEDLVVTPNHILVL 69 MTEWAGFRVDKDQLYL 526 DFLVLHNS 536
Aca-NAm1 PRP8 CLAKGTQLLRYDG 13 KEDLVVTPNHILVL 69 MTEWAGFRVDKDQLYL 485 DFLVLHNS 495
Ade-ER3 PRP8 CLAKGTQLLRYDG 13 KEDLVVTPNHILVL 69 MTEWAGFRVDKDQLYL 517 DFLVLHNS 527
Ade-SLH14081 PRP8 CLAKGTQLLRYDG 13 KEDLVVTPNHILVL 69 MTEWAGFRVDKDQLYL 517 DFLVLHNS 527
Afu-Af293 PRP8 CLAKGTRLLRYDG 13 KEDLVVTPNHILVL 69 ATEWAGFRVDKDQLYL 810 DYLVLHNS 820
Afu-FRR0163 PRP8 CLAKGTRLLRYDG 13 KEDLVVTPNHILVL 69 ATEWAGFRVDKDQLYL 810 DYLVLHNS 820
Afu-NRRL5109 PRP8 CLAKGTRLLRYDG 13 KEDLVVTPNHILVL 69 ATEWAGFRVDKDQLYL 810 DYLVLHNS 820
Agi-NRRL6136 PRP8 CLAKGTRLLRCDG 13 QEDLVVTPNHILVL 69 STEWAGFRVDKDQLYL 158 DYLVLHNS 167
Ani-FGSCA4 PRP8 CLANGTQLLRYDG 13 KEDLVVTANHILVL 69 ATEWAGFRVDKDQLYL 596 DYVVLHNS 605
Avi PRP8 CLAKGTRLLRYDG 13 IEDLVVTPNHILVL 69 TTEWAGFRVDKDQLYL 160 DYLVLHNS 170
Bci PRP8 CLAWDTKLLRYDG 13 KEDLVVTGNHILVL 69 ATNWAGFRVDKDQLYL 829 DYLVLHNS 839
Bde-JEL197 RPB2 CLSGDTEVVLGNG 13 GRVIKADPEHPLFA 75 RLYDFNTV*SQNHSFF 480 NSIVSHNC 489
Bde-JEL423 PRP8-1 CFAPGTLVRMANG 13 ASGFTCNSRHDLII 85 FGFELEPLQSSAPHFL 456 SFVVVHNC 466
Bde-JEL423 PRP8-2 CFAGHTSLLLADG 13 GDELVVTGNHILCL 68 QPYYGFKV*DGNQRFL 456 DFMVLHNS 466
Bde-JEL423 RPC2 CLSGDTEVVLGNG 13 GRVIKADPEHPLFA 75 RLYDFNTV*SQNHSFF 480 NSIVSHNC 489
Bde-JEL423 eIF-5B CFGRDTPLLMADG 13 HDAFVCNKEHILVM 73 GEYFGFTVMGPNSRFL 410 DFTVTHNT 420
Bfu-B05 PRP8 CLAWDTKLLRYDG 13 KEDLVVTGNHILVL 69 ATNWAGFRVDKDQLYL 802 DYLVLHNS 812
CIV RIR1 CVAPETMILTEDG 13 GCTLSCTPEHKFII 68 RVDDTYC**FTEPINH 329 NGILTGQC 340
CV-NY2A ORF212392 CLHPETDVITFSG 13 GEPWKCNETHVLSL 68 VGDYVGPVLDKDHRYL 382 DFTVTHNT 392
CV-NY2A RIR1 CVAGDTKILTSSG 13 GTELRCTPYHKFYI 68 DTYCFN**EPKRHMGV 328 GVITGGQC 337
CZIV RIR1 CVVGETLVLTQNG 13 GTSIICTPYHNFLS 68 DTYCFS**EPLNNAGV 131 NGILTGQC 140
Cba-WM02.98 PRP8 CLQNGTRLLRADG 13 LEDLVCTHNHILSL 68 PTKWSGFVVDKDSLYL 161 DYLVLHNS 171
Cba-WM728 PRP8 CLQNGTRLLRADG 13 LEDLVCTHNHILSL 68 PTKWSGFVVDKDSLYL 161 DYLVLHNS 171
Ceu ClpP CLTSDHTVLTTRG 13 GVDLFVTPNHRMYV 73 PVYCLTG***PNNVFY 445 KAVWTGNS 457
Cga PRP8 CLQNGTRLLRADG 13 LEDLVCTHNHILSL 68 PTKWSGFVVDKDSLYL 161 DYLVLHNS 171
Cgl VMA CFAKGTQVLMADG 13 DLSYTCNSNHTLVL 70 YGVTLD**DDSDHQFL 406 NLVLVHNC 416
Cla PRP8 CHAEGTELIKFDR 13 VESLVVTDNHIMML 72 STPWYGFAVDSDRQYL 513 DWMVLHNS 523
Cmo ClpP CLTSDHTVLTTRG 13 GVDLFVTPNHRMYV 73 PVYCLTV***PNSVFY 443 KAVWTGNS 457
Cmo RPB2 (RpoBb) CLTPDHDVLTTKG 13 NINLLVTPNHRMYI 73 PVFCLTV***PNEVFY 683 IPVWTGNS 696
Cne-A PRP8 (Fne-A PRP8) CLQNGTRLLRADG 13 LEDLVCTHNHILSM 69 PTKWSGFVVDKDSLYL 162 DYLVLHNS 172
Cne-AD PRP8 (Fne-AD PRP8) CLQNGTRLLRADG 13 LEDLVCTHNHILSM 69 PTKWSGRVVDKDSLYL 163 DYLVLHNS 173
Cne-JEC21 PRP8 CLQNGTRLLRADG 13 LEDLVCTHNHILSM 69 PTKWSGRVVDKDSLYL 163 DYLVLHNS 173
Cpa ThrRS CLSEDMRIQTDKG 13 GVSLLVTEDHDMYV 86 RVWCVTV**PTGLIVA 160 KPVVIGNC 183
Cre RPB2 CLSEEHQVLTNEG 13 GLSLVVTPGHDMYL 92 RTWCVS****LPHTYI 408 LPTILGNC 432
CroV Pol SVIGDTPLLLKNF 13 NGEVIVTDEHSLLN 90 YVYDLTT***ENHHFH 337 GSIIVHNT 348
CroV RIR1 CFTPDTPIFTNDG 13 LEEIKCTKEHDILI 70 YVYDLNI**EENHNYL 327 SSGIVHNS 336
CroV RPB2 CQKYDTLVLTHLG 13 SIDIECTINHKLYC 73 KVYCIEV**PDSHIYY 132 PPVWIGNS 147
CroV Top2 CISSDTNVLIWNS 13 GENYSVNNNHTLTL 69 DYVSITVDTTTNQRFL 378 DFTVTHNC 388
Cst RPB2 CLTPSHEVLTENG 13 EIELQVTQEHYMWV 83 SVHCVEV**PEPHLFY 350 KGVWTGNS 363
Ctr ThrRS CLSEDMRVQTNKG 13 SFSLFVTDNHDMYV 85 RVWCVTV**PTGLIIV 323 RPTIVGNC 346
Ctr VMA CFTKGTQVMMADG 13 LMDFTVSADHKLIL 78 YGITLA**EETDHQFL 462 NMALVHNC 472
Ctr-MYA3404 VMA CFTKGTQVMMADG 13 LMDFTVSADHKLIL 78 YGITLA**EETDHQFL 462 NMALVHNC 472
Ddi RPC2 CLHPDTIITMSNG 13 GKEIICTNDHRFLT 78 EISDFTT*ESDYHSMI 456 NGFVSHNC 465
Dhan GLT1 CLASDTLVRTSEG 13 RVSFKCTPDHHLEL 73 EDGEFRAIEVSGGVFQ 599 NRLVVANC 608
Dhan VMA CFAKGTEVLMADG 13 RIAFTCNAKHELVV 76 YGVTLP**DNSDHQFM 386 NQAVVHNC 395
Eni PRP8 CLANGTQLLRYDG 13 KEDLVVTANHILVL 69 ATEWAGFRVDKDQLYL 596 DYVVLHNS 606
Eni-FGSCA4 PRP8 CLANGTQLLRYDG 13 KEDLVVTANHILVL 69 ATEWAGFRVDKDQLYL 596 DYVVLHNS 606
Fte RPB2 (RpoB) CLTPDHDVLTAEG 13 NLSLLVTLNHRMYV 73 KVFCLSV***PNEVFY 365 LPVWTGNS 378
Gth DnaB CLSYATNQPYFLK 13 ISVIVSTVEHYVLT 86 NVYDFWI*PKTNNFFV 153 NALLVHNS 161
HaV01 Pol SVTKETPLMLRTM 13 NGYVEVTEDHSLIS 98 YVYDVET**EDGIFHA 223 GEIIVKNT 233
Hca PRP8 CLAKGTQLLRYDG 13 KEDLVVTPNHILVL 69 MTEWAGFRVDKDQLYL 525 DFLVLHNS 535
IIV6 RIR1 CVAPETMILTEDG 13 GCTLSCTPEHKFII 68 RVDDTYC**FTEPINH 329 NGILTGQC 340
Kex-CBS379 VMA CFAKGTQVMMADG 13 LMNYVCSGNHKIVM 76 YGITVP**DNTDKQYL 493 SMALVHNC 503
Kla-CBS683 VMA CFSKGTEVMMGDG 13 KISFQCNSSHKLVL 74 FGVTLA**EESDHKFL 401 NMTLVHNC 411
Kla-IFO1267 VMA CFSKGTEVMMGDG 13 KISFQCNSSHKLVL 74 FGVTLA**EESDHKFL 401 NMTLVHNC 411
Kla-NRRLY1140 VMA CFSKGTEVMMGDG 13 KISFQCNSSHKLVL 74 FGVTLA**EESDHKFL 401 NMTLVHNC 411
Lel VMA CFTKGTQVMMADG 13 SLNFTVSADHKLVL 71 YGITLS**ETSDHMFL 412 NLALVHNC 422
Mca-CBS113480 PRP8 CLANGTMLLRYDH 13 KEDLVVTANHILVL 69 ATGWAGFRVDGDQLYL 542 DYLVLHNS 552
Nau PRP8 CLAKGTRLLRYDG 13 VEDLVVTPNHILVF 69 TTEWAGFRVDKDQLYL 155 DYLVLHNS 165
Nfe-NRRL5534 PRP8 CLAKGTRLLRYDG 13 VEDLVVTPNHILVL 69 ATEWAGFRVDKDQLYL 146 DYLVLHNS 156
Nfi PRP8 CLAKGTRLLRYDG 13 KEDLVVTPNHILVL 69 TTEWAGFRVDKDQLYL 508 DYLVLHNS 518
Ngl-FR2163 PRP8 CLAKGTRLLRYDG 13 VEDLVVTPNHILVL 69 TTEWAGFRVDKDQLYL 146 DYLVLHNS 156
Ngl-FRR1833 PRP8 CLAKGTRLLRYDG 13 IEDLVVTPNHILVL 69 STEWAGFRVDKDQLYL 160 DYLVLHNS 170
Nqu PRP8 CLAKGTRLLRYDG 13 IEDLVVTPNHILVL 69 TTEWAGFRVDKDQLYL 160 DHLVLHNS 170
Nspi PRP8 CLAKGTRLLRYDG 13 IEDLVVTPNHILVL 69 STEWAGFRVDKDQLYL 160 DYLVLHNS 170
Pabr-Pb01 PRP8 CLAKGTLLLRYDG 13 KEDLVVTPNHILVL 69 TTEWAGFRVDQDQLYL 550 DFLVLHNS 560
Pabr-Pb03 PRP8 CLAKGTLLLRYDG 13 KEDLVVTPNHILVL 69 ATEWAGFRVDQDQLYL 564 DFLVLHNS 574
Pan CHS2 CLSPDTMVRTTNG 13 KSSFTCTPDHIMTL 73 GEFRLI**EVSGELFQ 640 DRTVVHNC 650
Pan GLT1 CLHPSTTVRTLAG 13 KKSFKCTPDHILPL 73 DDYRAI**QVSGSLFQ 673 NGLVTHNC 683
Pbl PRP8-a CFSGDTFLLLADG 13 GEALEVTGNHILCL 68 PQTYYGFRIDGNQRFL 189 DGLVVHNS 199
Pbl PRP8-b CFAGDTFLLLADG 13 GEALEVTGNHILCL 68 PQTYYGFRIDGNQRFL 189 DGLVVHNS 199
Pbr-Pb18 PRP8 CLAKGTLLLRYDG 13 KEDLVVTPNHILVL 69 ATEWAGFRVDQDQLYL 564 DFLVLHNS 574
Pch PRP8 CLAKGTRLLRCDG 13 KEDLVVTPNHILVF 69 KTEWAGFRVDKDQLYL 148 DYLVLHNS 158
Pex PRP8 CLAKGTRLLRYDG 13 KEDLVVTPNHILVL 69 ETEWAGFRVDKDQLYL 153 DYLVLHNS 163
Pgu GLT1 CLASDTLVRTTQG 13 LVSFKCTPDHHLEL 73 GEFRAI**EVSGGKFQ 544 NGLQIANC 554
Pgu-alt GLT1 CLASDTLVRTTQG 13 LVSFKCTPDHHLEL 73 GEFRAI**EVSGGKFQ 544 NGLQIANC 554
Pno GLT1 CLETATVVRTKQG 13 VDSFTCTPDHELLL 73 GSYRGI**EVSGHEFQ 626 NRTMVSNC 636
Pno RPA2 CLSADHEVLTSTG 13 DMDAVCNESHRWYL 73 EYSDNDKIQEVIDAAQ 449 KPFFTGNC 457
Ppu DnaB CISKFSHIMWSHV 13 EKYLELTSNHKILT 74 NVFDFAA**NPIPNFI 142 NNIIVHNS 151
Pst VMA CFAKGTKVLMANG 13 TASYTCNATHKLVL 77 YGITLS**EDSDHQFL 440 NLALVHNC 450
Ptr PRP8 CLQNGTKLLRYDA 13 KEDLVVTSNHILVL 69 PTGWSGFKVDQDQLYL 835 DYIVLHNS 845
Pvu PRP8 CLAKGTRLLRYDG 13 KEDLVVTPNHILVL 69 KTEWAGFRVDKDQLYL 152 DYLVLHNS 162
Pye DnaB CISKFNYLQTSLY 13 GKYIQLTSNHKLLT 76 IVFDLEC**KPLCNFI 140 NNFIVHNS 149
Sas RPB2 CLTPDHEVLTERG 13 HVSLITTPNHRMWT 72 KVHCIEV***PGHVFY 342 KAVWTGNS 355
Sca-CBS4309 VMA CFAKGTEVLMADG 13 LMNYVCSGNHKLVL 78 YGITLP**DETDKQYL 508 SLALVHNC 518
Sca-IFO1992 VMA CFAKGTEVLMADG 13 LMNYVCSGNHKLVL 78 YGITLP**DETDKQYL 508 SLALVHNC 518
Scar VMA CFAKGTTVLMADG 13 LLKFTCNSTHELVV 83 YGITLS**DDSDHQFL 445 NQVVVHNC 455
Sce VMA CFAKGTNVLMADG 13 LLKFTCNATHELVV 83 YGITLS**DDSDHQFL 445 NQVVVHNC 455
Sce-DH1-1A VMA CFAKGTNVLMADG 13 LLKFTCNATHELVV 83 YGITLS**DDSDHQFL 445 NQVVVHNC 455
Sce-JAY291 VMA CFAKGTNVLMADG 13 LLKFTCNATHELVV 83 YGITLS**DDSDHQFL 445 NQVVVHNC 455
Sce-OUT7091 VMA CFAKGTNVLMADG 13 LLKFTCNATHELVV 83 YGITLS**DDSDHQFL 445 NQVVVHNC 455
Sce-OUT7112 VMA CFAKGTNVLMADG 13 LLKFTCNATHELVV 83 YGITLS**DDSDHQFL 445 NQVVVHNC 455
Sce-YJM789 VMA CFAKGTNVLMADG 13 LLKFTCNATHELVV 83 YGITLS**DDSDHQFL 445 NQVVVHNC 455
Sda VMA CFAKGTQVMMADG 13 VMDYVCSGNHKLVL 79 YGITLP**DSTDKQYL 492 SLALVHNC 502
Sex-IFO1128 VMA CFAKGTQVMMADG 13 LMNYVCSGNHKIVM 76 YGITVP**DNTDKQYL 490 SMALVHNC 500
She RPB2 (RpoB) CLTVDHEVLTTKG 13 NLDLLVTLNHRMYV 83 AVYCLSV***PNEIFY 378 LSVWTGNS 391
Sja VMA CFAKGTEVLMANG 13 NLSYTCNATHKLVL 77 YGVTLA**EDSDHQFL 467 NLTLVHNC 477
Spa VMA CFAKGTNVLMADG 13 LLKFTCNATHELVV 83 YGITLS**DDSDHQFL 445 NQVVVHNC 455
Spu PRP8 CLAAGTKVMVVRN 13 SQEYTVTEGHLLSL 76 TYFRFSV**DGYQSRF 463 DWTVVHNC 474
Sun VMA CFEKGTEVLMADG 13 LMDYVCSGNHKFVL 75 YGVTLP**DATDKQYL 405 SLALVHNC 415
Tgl VMA CFAKGTPVMMHDG 13 LFEYTCNATHKLVV 84 YGITLS**ENSDHQFM 447 NQLVVHNC 457
Tpr VMA CFAKGTKVLLHDG 13 LFEYTCNATHKLVV 84 YGLTLA**NGTDHQFM 446 NQLVVHNC 456
Ure-1704 PRP8 CLAKGTRLLRYDR 13 VEDLVVTPNHILVF 69 ETEWAGFRVDQDQLYL 171 DYLVLHNS 181
Vpo VMA CFAKGTEVMMADS 13 LFSFVCNATHQLIV 74 YGITLP**EYSDHQFM 434 NQVVVHNC 434
WIV RIR1 CVVGETLILTENG 13 GIFIVCTEYHRFLV 68 NTYCFT**EQLNNAGV 130 NGILTSNC 139
Zba VMA CFAKGTEVMMHDG 13 LFEYNCNATHKLVV 84 YGITLA**KESDHQFL 447 NQLVVHNC 457
Zbi VMA CFAKGTEVMMSDA 13 LSEYTCNATHKLVV 81 YGLTLS**NDSDHQFL 441 NQLVVHNC 451
Zro VMA CFAKGTEVMMSDG 13 LFEYTCNATHKLVV 83 YGLTLS**NESDHQFL 441 NQLVVHNC 451 |
Eubacteria |
Intein Block A Block B Block F Block G
AP-APSE1 dpol CLAKGTLVLTITG 13 AYGVGMTADHQVLT 62 EVYDLIN*CGPRNRFV 294 GPLIVHNC 307
AP-APSE2 dpol CLAKGTLVLTITG 13 AYGVGMTADHQVLT 62 EVYDLIN*CGPRNRFV 294 GPLIVHNC 307
AP-APSE4 dpol CLAKGTLVLTITG 13 AYGVGMTADHQVLT 62 EVYDLIN*CGPRNRFV 294 GPLIVHNC 307
AP-APSE5 dpol CLAKGTLVLTITG 13 AYGVGMTADHQVLT 62 EVYDLIN*CGPRNRFV 294 GPLIVHNC 307
AP-Aaphi23 MupF CFPGQSELKGLPR 13 GTVLLATPNHPILT 47 QASCHIYNLQTVSGYY 316 NSVFVSNC 326
Aae RIR2 CFIEGTEVLTKRG 13 NWEVVATEGHEFIV 75 KVYCVSV**PKGNIVV 335 SVCIAGNC 347
Aave-AAC001 Aave1721 CVDDTTEALTQRG 13 TLDMLMTPDHRVVH 73 RVWCPIV*PGTSTWVA 322 MPFITHNT 334
Aave-AAC001 RIR1 CVTADTWVMTDAG 13 GHALRLTEDHLVRR 70 DVYDVTVA**DCHAFD 380 NGLCVHNC 389
Aave-ATCC19860 RIR1 CVTADTWVMTDTG 13 GYALRLTEDHPVRR 70 DVYDVTVA**DCHAFD 380 NGLYVHNC 389
Aba Hyp-02185 CFGKGTLIKLANG 13 GKAHTFNKSHILCL 69 KYYGFV**LDPDPFFL 140 DDLVLHNT 150
Ace RIR1 CQPYSAPVSTPDG 13 GHVLDVTPDHLVWQ 71 PVYDIQT***ESGEYL 145 DGIRVHNC 154
Aeh DnaB-1 CIMAGSRLVDPRT 13 GREIATTLTHPFLT 76 QVYDLTV**DGTHNFV 493 EDVCVHNT 502
Aeh DnaB-2 CVTGDTRVLLADG 13 GRTIRCTPEHRLRG 74 EVFDLTV**PGNACWL 410 DGIVSHNS 419
Aeh RIR1 CVTADTWVQTADG 13 GYRLKLTADHRVRR 70 EVYDVQV**PGINTFD 369 NGLHAHNC 378
AgP-S1249 MupF CFPGQSELKGLPR 13 GTVLLATPNHPILT 47 QASCHIYNLQTVSGYY 316 NSVFVSNC 326
Aha DnaE-c NVYDVCV**ETDHNFV C27 NGLVASNC C37
Aha DnaE-n CLSYDTEIWTVEY N13 GRKIRATKDHKMMT N76
Alvi-DSM180 GyrA CFTGDTAIKLADG 13 GDVVRCTPDHRFML 79 DTYDITV**DHHHNFL 511 CGVFVHNS 521
Ama MADE823 NIAHSTPVLTANR 13 GEKIRCHANHEWTV 68 KGHCIQV*DSPDGLYL 334 KLVATHNS 345
Amax-CS328 DnaX CLTGDALILSDRG 13 QTEIKCTGNHLIRT 73 HVYDIEV**EHNHNFV 128 NGLLVHNC 137
Aov DnaE-c NVYDIGV**EHHHNFA C27 NGLIASNC C37
Aov DnaE-n CLSADTEILTVEY N13 GSIIRATKDHKFMT N76
Apl-C1 DnaX CLTGDALILSDRG 13 QTEIKCTGNHLIRT 73 HVYDIEV**EHNHNFV 128 NGLLVHNC 137
Arsp-FB24 DnaB GLALDTPIPAPKG 13 GTSLVASDGNLWQA 69 LVRGIRV*DTKDSLFQ 322 GCQLTHNT 333
Asp DnaE-c NVYDIGV**RRDHNFF C27 NGLIASNC C37
Asp DnaE-n CLSYDTEVLTVEY N13 GSIIKATKDHKFMT N76
Ava DnaE-c NVYDIGV**GRDHNFF C27 NGLIASNC C37
Ava DnaE-n CLSYDTEVLTVEY N13 GSIIKATKDHKFMT N76
Avin RIR1 BIL CFAPETLVHTADG 13 VEPIEVTAGHPFYA 70 FVFDLKV**EGDESYM 370 TSGLAHNG 379
Bce-MCO3 DnaB AQPLDARVRTLTG 13 GRSAECCDEHLWCV 68 ATQCISV*SHPSRLYV 338 DYVVTHNT 348
Bce-PC184 DnaB AQPLDARVRTLTG 13 GRSAECCDEHLWCV 68 ATQCISV*SHPSRLYV 339 DYVVTHNT 348
Bse-MLS10 TerA QLALDTPIPTPDG 13 GQSIVAGERHLWQV 69 PMRCIQV*DSPSRLYL 322 SMVPTHNS 333
BsuP-M1918 RIR1 CVTGETLLLTENG 13 GYEIRATEWHKFYV 83 DVYDTTQ**EDYHSLI 377 NGIVTGNC 386
BsuP-SPBc2 RIR1 CVTGETLLLTENG 13 GYEIRATEWHKFYV 83 DVYDTTQ**EDYHSLI 377 NGIVTGNC 386
Bvi IcmO PQPLHSLVRMADG 13 GRSVEAARVHHWPV 69 PARCLVV*ADEMHCYI 133 HDIVTHNC 143
CP-P1201 Thy1 CYSSDTEVLTSEG 13 GVDLLVTPNHKMLA 72 TVYCATV**PNHTLYV 334 PVWSGGNS 346
Cag RIR1 CVTADTLIATDRG 13 GYQLKLTGDHVVFT 69 AVFDLTE*PETDHFIA 363 NGIGVHNC 371
Cau SpoVR CLHGDSLIVTDHG 13 GFTLTGSHNHRIML 70 DVYDISV**TATHRYA 268 QGFINHNS 277
CbP-C-St RNR CFDGQQKTLTKSS 13 NKEILVTEDHINVT 81 YVYCFEMKNIEEPYFT 321 NGIITHNC 331
CbP-D1873 RNR CFDGQQKTLTKSS 13 NKELLVTEDHINVT 81 YVYCFEMKNIEEPYFT 321 NGVITHNC 331
Cbu-Dugway DnaB CVTGDTLICLADG 13 GRSIKATAEHRLLA 71 EVYDLTV**PKYASWL 138 DGVVSHNS 147
Cbu-Goat DnaB CVTGDTLICLADG 13 GRSIKATAEHRLLA 71 EVYDLTV**PKYASWL 138 DGVVSHNS 147
Cbu-RSA334 DnaB CVTGDTLICLADG 13 GRSIKATAEHRLLA 71 EVYDLTV**PKYASWL 138 DGVVSHNS 147
Cbu-RSA493 DnaB CVTGDTLICLADG 13 GRSIKATAEHRLLA 71 EVYDLTV**PKYASWL 138 DGVVSHNS 147
Cce Hyp1-Csp-2 CFPAKTLILTDQG 13 ENTICCTPDHPFAT 80 RVYNFTV**EDNHNYI 395 TPVLVHNC 409
Cch RIR1 CVTADTLIATDRG 13 GYQLKLTGDHVVFT 69 AVFDLTE*PETDHFIA 363 NGIGVHNC 371
Ccy Hyp1-Csp-1 CFTGDTLIPLVDG 13 GEEIKCTPDHQFML 76 DVYCLTV**PEYNNFA 185 AGVFVHNC 195
Ccy Hyp1-Csp-2 CFPAKTLILTEKG 13 ENTICCTPNHPFAT 80 EVYNFTV**EDNHNYI 396 TPVLVHNC 410
Cfl-DSM20109 DnaB ALALDTPLPTPTG 13 GSTIVADAQHQWAT 69 PVRCVEISHQSHLYL 310 AMIPTHNS 321
Chy RIR1 CVTGDTLVFTDKG 13 GLEIKVTEEHKIFT 67 EVFDITA**PPKYTWI 337 NGILSLDC 346
Ckl PTerm ALDLDTPIDTPTG 13 GEFIIADTEHIWTV 69 PVKCIAV*EDEKKLYL 392 NHTATHNT 403
Cra-CS505 DnaE-c DVYDIGV**AKDHNFI C27 NGLVASNC C37
Cra-CS505 DnaE-n CLSYETEVLTLEY N13 GSTIRATKDHKFMT N76
Cra-CS505 GyrB CFVGNTLVSLTDG 13 DQVLICTPDHLFML 80 DVYDLEV**PHTHNFA 144 AGVFVHNS 154
Csp-CCY0110 DnaE-c NVYDIGV**EKDHNFL C27 NNLIASNC C37
Csp-CCY0110 DnaE-n CLSYDTEILTVEY N13 GETIRATKDHKFMT N76
Csp-PCC7424 DnaE-c PVYDIGV**EKDHNFL C27 DGLIASNC C37
Csp-PCC7424 DnaE-n CLSYETQIMTVEY N13 GSTIRATKDHKFMT N76
Csp-PCC7425 DnaB CLTGDSLITLADT 13 GRAIRATGNHKFLT 77 DVFDLTV**PEHHNFV 421 NNIIVHNS 430
Csp-PCC7822 DnaE-n CLSYDTEILTVEY N13 GSIIRATKDHKFMT N76
Csp-PCC8801 DnaE-c FVYDIGVA**QDHNFL C27 NGSIASNC C37
Csp-PCC8801 DnaE-n CLSYDTEILTVEY N13 GSILRATKDHQFMT N76
Cth ATPase BIL CFVAGTMILTVAG 13 GDVIKTTFEHLFYA 72 KVYNFQV**DDFHTYH 125 NGVLVHNV 136
Cth-ATCC27405 TerA QLALDTPIPTPDG 13 GTSIVAGERHLWKV 69 KMRCIQV*DSPSRLYL 323 SMIPTHNS 334
Cth-DSM2360 TerA QLALDTPIPTPDG 13 GSSIIAGARHLWKV 69 PMRCIQVSSPSRQYL 329 SMVPTHNS 340
Cwa DnaB CLATNSEIILADG 13 GRYIETTLTHPYLT 75 QVYDLTI**PKTHNFV 488 NDICVHNT 497
Cwa DnaE-c KVYDIGV**EKDHNFL C27 NGSIASNC C37
Cwa DnaE-n CLSYDTEILTVEY N13 GSKIKATKDHKFMT N76
Cwa PEP CFDGKTKILTNQG 13 DNTLRLTPDHKMVN 81 DVYNITV**AEHHNYV 381 TPVVVCNC 395
Cwa RIR1 CVAPETKILTDRG 13 GESLDCTYYHKFHV 68 CRYDDTYCFSEPKRHL 337 NGILTGQC 348
Daud RIR1 CVTGDTWVTTGAG 13 GYTVRLTADHMILR 70 DVYDVQV**PGINAFD 367 NGIVAHNC 376
Dge DnaB CVTADTLIDVPGT 13 GRVVETTPHHPFLG 76 QVYDLTV**PGDANFI 394 ADICLHNT 402
Dha-DCB2 RIR1 CVTGDTWVLTEEG 13 GYELKVTADHLVRV 80 EVFDAQV**PGINAFD 358 NGIYVHNC 367
Dha-Y51 RIR1 CVTGDTWVLTEEG 13 GYELKVTADHLVRV 80 EVFDAQV**PGINAFD 358 NGIYVHNC 367
Dpr-MLMS1 RIR1 CVTADTFVMTAEG 13 GYSVRLTADHPVMQ 70 EVFDIQV**PGVHAFD 368 NGLMLHNC 377
Dra RIR1 CVTADTWVSTAFG 13 GYELRLTGNHQLLK 69 AVYDVTV**EQVHAFD 308 NGVLAHNC 367
Dra Snf2-c PAQCIAV*DAPDHLYV C148 GYIVTHNT C158
Dra Snf2-n AQPLDAKVLTPLG 13 GASVEADAEHLWNV N68
Dra-ATCC13939 Snf2 AQPLDAKVLTPLG 13 GASVEADAEHLWNV 68 PAQCIAV*DAPDHLYV 334 GYIVTHNT 344
Dth UDP GD CLLGKEKILVKNS 13 NRKLIVTEKHPMLR 98 DVYSLEV**ENTHTFA 472 SGIYVHNC 482
Dvul ParB CQPAGTMVQKVID 13 GRVTRATPEHRFTV 86 YSMDVD***KDLHYVA 281 DGLVTHNC 289
EP-Min27 Primase ACPLNEPILLADG 13 GRYVDCAGDHLWEV 69 ECLCIMV*DHPRHLYV 333 GYVATHNT 343
Fal DnaB ALALGTALPTPTG 13 GSVIVADGQHQWIT 69 PVRCVEVD*SPDHLYL 398 TCIPTHNS 409
Fsp-CcI3 RIR1 CQPYDALVSTPSG 13 GHALDVTADHLVWR 71 PVYDIQT***DSGEYL 286 AGLRVHNC 295
Gob DnaE CVVAGTEVTDAET 13 GKSITATDNHPFRV 77 DTYDLTV**DEDHNFV 438 NGLIVHNS 447
Gob Hyp CQPAGTQVAKVIK 13 AVTGITSRRHTGNL 64 EVWSMDV*ERDKHYVA 280 DGIVVHNC 288
Gvi DnaB CCAADTPIADPVT 13 GREVKTTLTHPYLT 80 QVYDLTV**PVTHNFV 250 ADICLHNT 259
Gvi RIR1-1 CFAAGTLLHTEQG 13 GYSVEVTANHKMAR 69 RVYDIEV**EGMHLLS 405 NGIYTSNS 414
Gvi RIR1-2 CVTADTWVHTGDG 13 GHQLRLTGNHQVLK 70 EVYDCTV**PGPARFD 359 NGLVVHNC 368
Hhal DnaB CLAYDAEIVQADG 13 GRRIETTLTHPFLT 75 QVYDLTI**PETHNFI 484 NDVCVHNT 493
Kfl-DSM17836 DnaB ALALDTPLPTPSG 13 GTTLVADAEHQWVV 69 PVRCVEV*DNPDHLYL 146 SMVPTHNS 157
Kra DnaB CLTAGTRVLRADT 13 GKTVRATANHPFLT 78 QVYDATV**LGGHNFV 420 DGIAVHNS 429
LLP-KSY1 PolA CFSGDTEILTPYG 13 VYEDTNTSIHATGN 67 DVYCVNV***PTHNIV 291 KVSIQGNC 304
LP-phiHSIC Helicase CHAYGHDIMMSDG 13 YIRSSSTFKHRSKL 102 GVGDYYGF/DGDHLYL 330 DFVRHHNC 340
Lsp-PCC8106 GyrB CFTGDTLVPLADG 13 GAEIKCTPDHQFML 76 DVYCLTV**PEYHNFA 222 DGVFVHNC 232
MP-Be DnaB PLALNTEVPTPSG 13 GTEITASASHGWTT 69 PVKCIGI*DTEDHLFQ 331 SRILTHNT 342
MP-Be gp51 CSWTNARAVTRRG 13 EINATITANHRVVG 72 EVWCLRV**PNGRFFI 306 KIHLTGNS 318
MP-Catera gp206 SLACSTPILTTNG 13 GQEVVTDAEHLWQV 69 PVRCITV*AHESSLYV 321 GFVPTHNT 332
MP-KBG gp53 CSWTNARAVTRRG 13 EINATITANHRVVG 72 EVWCLRV**PNGRFFI 306 KIHLTGNS 318
MP-Mcjw1 DnaB ALDVETPILTGNG 13 GAELVASDHHLWAV 68 ETVCIQI*DHPSHVFL 320 SLTPTHNT 332
MP-Omega DnaB ALAIDTPILSERG 13 GQTIVADEDHLWTV 68 PTRCITV*DNDSRLYV 330 GFVPTHNT 341
MP-U2 gp50 CSWTNARAVTRRG 13 EINATITANHRVVG 72 EVWCLRV**PNGRFFI 306 KIHLTGNS 318
Maer-NIES843 DnaB CLAGDSLVELAAP 13 GRTIRATANHKFLT 77 EVYDLTV**DKLHNFI 134 NNIIVHNS 143
Maer-NIES843 DnaE-c PVYDIGV**EKDHNFL C27 NGLIASNC C37
Maer-NIES843 DnaE-n CLGGETLILTEEY N13 GQTIQATKDHKFMT N76
Mau-ATCC27029 GyrA CLAADVRVRTVDG 13 GYELTGTHNHPVLC 78 PVYSIRVD*TEDHSFV 412 DGFVSHNT 421
Mav-104 DnaB ALALDTPLPTPTG 13 GTVIVADAAHQWLT 70 AVRCVEV*DNDSHMYL 327 AMVPTHNS 338
Mav-ATCC25291 DnaB ALALDTPLPTPTG 13 GTVIVADAAHQWLT 69 AVRCVEV*DNDSHMYL 327 AMVPTHNS 338
Mav-ATCC35712 DnaB ALALDTPLPTPTG 13 GTVIVADAAHQWLT 70 AVRCVEV*DNDSHMYL 327 AMVPTHNS 338
Mav-PT DnaB ALALDTPLPTPTG 13 GTVIVADAAHQWLT 69 AVRCVEV*DNDSHMYL 407 AMVPTHNS 418
Mbo Pps1 CLPAGELITTADG 13 ANAFSVTAEHPLLA 71 PVYNLDV**ENPDSYL 351 YGFAVHNC 360
Mbo RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mbo SufB (Mbo Pps1) CLPAGELITTADG 13 ANAFSVTAEHPLLA 71 PVYNLDV**ENPDSYL 351 YGFAVHNC 360
Mbo-1173P DnaB CLTASTRILRADT 13 GREVEATGSHPFMK 77 HVFDGTV**SGTHNFV 408 NGISLHNS 417
Mbo-AF2122 DnaB CLTASTRILRADT 13 GREVEATGSHPFMK 77 HVFDGTV**SGTHNFV 408 NGISLHNS 417
Mca MupF CFPAETPVRAAAR 13 GHRLTLTANHPVLT 45 HVYDFET**ETGLIMA 307 GGVIVHNC 315
Mca RIR1 CVTADTWVMTASG 13 GHTLRLTANHPVLR 70 AVYDVTV**ADVHAFD 372 NGLYVHNC 381
Mch RecA CFNYSTRVQLADG 13 RSQFAATPNHLIRT 83 NRFDIEV**EGNHNYF 356 DGVMVHNS 365
Mcht-PCC7420 DnaE-1 CLSGSTEIIDAET 13 NRKIKATADHRFYS 81 EVFDLSI**SQTHNLI 184 NDFIAHNC 193
Mcht-PCC7420 DnaE-2c PVYDIGV**ERDHNFL N27 NGSVASNC N37
Mcht-PCC7420 DnaE-2n CLSYDTQILTVEY N13 GATIRATKDHKFMT N76
Mcht-PCC7420 GyrB CFDGDTRVALADG 13 GETLICTPDHPFMV 80 DVYDIEV**PHTHNFA 206 SGVFVHNS 216
Mcht-PCC7420 RIR1-1 CLPEGSLVHTESG 13 DGYLDCTPDHKVAV 66 PTYDI**EVATIHEFV 386 EGILVSNS 395
Mcht-PCC7420 RIR1-2 CVTADTWVHTEFG 13 GVSLRLTGNHQILR 70 SVYDCTV**PGVSRFD 333 NGIVAHNC 342
Mex Helicase CFAAGTLIKTPKG 13 GTSIVCTHDHPFFC 66 AVYNLRV**SGHPSYF 262 GGVLVHNC 271
Mex TrbC ALPLDALVHTPAG 13 GRTAEACPEHLWEV 68 QAACIRI*DHPDHLFI 356 DYVVTHNT 366
Mfa RecA CFSYGTRVQLADG 13 RSQFAATPNHLIRT 83 NRFDIEV**EGNHNYF 355 DGVMVHNS 364
Mfl GyrA CVTGDALVRLPFG 13 GYEVTGTANHPLLC 79 PVYSLRV*DTDDHSFL 412 NGFVSHNT 422
Mfl RecA CFAYGTRGALADG 13 KSQFAATPNHLIRT 83 NRFDIEV**EGNHNYF 356 DGVMVHNS 365
Mfl-ATCC14474 RecA CFNYSTRVQLADR 13 KSQFAATPNHLIRT 83 NRFDIEV**EGNHNYF 356 DGVMVHNS 365
Mfl-PYR-GCK DnaB ALALDTPLPTPTG 13 GTVLVADAEHQWLT 69 PVRCVEV*DNDDHLYL 407 SMIPTHNS 418
Mga GyrA CTTGDTLVRLPFG 13 GYEVTGTANHPLLC 79 PVYSLRV*DTDDHAFL 398 NGFVSHNT 421
Mga RecA CGSWYTNVTLADG 13 HASLAMTRNHLIRT 86 SRFDIEV**EGSHNYF 360 DGVMVHNS 369
Mga SufB (Mga Pps1) CLAGDTLWTANRG 13 RRSVRATDNHPMLV 73 PVYDIEV**DGPHNFV 357 EGLVVNHS 379
Mgi-PYR-GCK DnaB ALALDTPLPTPTG 13 GTVLVADAEHQWLT 69 PVRCVEV*DNDDHLYL 407 SMIPTHNS 418
Mgi-PYR-GCK GyrA CVTGDAMVRLPFG 13 GYEVTGTSNHPLLC 79 PVYSLRV*DTDDHSFI 412 NGFVSHNT 422
Mgo GyrA CLTGDALVRLPFG 13 GYEVTGTSNHPVLC 79 PVYSLRV*DSEDHAFL 412 NGFVSHNT 421
Min-1442 DnaB ALALDTPLPTPTG 13 GTVIVADAAHQWLT 69 AVRCVEV*DNGSHLYL 325 AMVPTHNS 336
Min-ATCC13950 GyrA CVTADALVRLPFG 13 GYEVTGTANHPLLC 79 PVYSLRV*DTEDHAFL 412 NGFVSHNT 421
Mkas GyrA CVTGDALVRLPFG 13 GYEVTGTANHPLLC 79 PVYSLRV*DTDDHAFL 412 NGFVSHNT 421
Mkas-ATCC12478 GyrA CVTGDALVRLPFG 13 GYEVTGTANHPLLC 79 PVYSLRV*DTDDHAFL 412 NGFVSHNT 421
Mle-Br4923 GyrA CVSGNSLVRLLFG 13 GYEITGTSNHPLLC 79 PVFSLHV*DTEDHSFL 412 NGFISHNT 421
Mle-TN DnaB ALALDTPLPTPTG 13 GTVIVADAQHQWPT 69 PVRCVEV*DNAAHLYL 135 GMVPTHNS 146
Mle-TN GyrA CVSGNSLVRLLFG 13 GYEITGTSNHPLLC 79 PVFSLHV*DTEDHSFL 412 NGFISHNT 421
Mle-TN RecA CMNYSTRVTLADG 13 KSQFAATPNHLIRT 83 NRFDIEV**EGNHNYF 357 DGVMVHNS 366
Mle-TN SufB (Mle Pps1) CLTADARINVKGK 13 GRALEATGNHQFLV 72 PTYDIQV**VGLENFV 378 NGIVAHNS 387
Mma GyrA CCTGDALVRLPFG 13 GYEVTGTSNHPLLC 79 PVYSLRV*DTDEHAFL 412 NGFVSHNT 421
Mmag Magn8951 BIL CFVAGTPVRMADG 13 SLDFFVTADHPFLT 68 VVYNLHL**IGNNTYV 133 SGYYVHNY 142
Msh RecA CMNYSTRVTLADG 13 KSQFAATPNHLIRT 83 NRFDIEV**EGNHNYF 356 DGVMVHNS 365
Msm DnaB-1 ALALDTPLPTPSG 13 GTAIVADAQHQWPT 69 PVRCVEV*DNPEHLYL 129 GMVPTHNS 140
Msm DnaB-2 CMTANTRILRADT 13 GREVEATANHPFLT 68 DVYDGTV**PGTHNFV 417 QGISAHNS 426
Msp-KMS DnaB ALALDTPLPTPDG 13 GTVIVADAQHQWLT 69 PVRCVEV*SNDSHMYL 312 SMVPTHNS 323
Msp-KMS GyrA CVTGDALVRLPLG 13 GYTVTGTENHPLLC 79 PVYSLRV*DTEDHAFI 413 NGFVSHNT 422
Msp-MCS DnaB ALALDTPLPTPDG 13 GTVIVADAQHQWLT 69 PVRCVEV*SNDSHMYL 312 SMVPTHNS 323
Msp-MCS GyrA CVTGDALVRLPLG 13 GYTVTGTENHPLLC 79 PVYSLRV*DTEDHAFI 413 NGFVSHNT 422
Mthe RecA CFDYSTRAQLADG 13 RARFAATPNHLIRT 83 NRYDIEV**EGNHNYF 357 DGVMVHNS 366
Mtu SufB (Mtu Pps1) CLPAGELITTADG 13 ANAFSVTAEHPLLA 71 PVYNLDV**ENPDSYL 351 YGFAVHNC 360
Mtu-C RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-CDC1551 DnaB CLTASTRILRADT 13 GREVEATGSHPFMK 77 HVFDGTV**SGTHNFV 408 NGISLHNS 417
Mtu-CPHL RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-Canetti RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-EAS054 RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-F11 DnaB CLTASTRILRADT 13 GREVEATGSHPFMK 77 HVFDGTV**SGTHNFV 408 NGISLHNS 417
Mtu-H37Ra DnaB CLTASTRILRADT 13 GREVEATGSHPFMK 77 HVFDGTV**SGTHNFV 408 NGISLHNS 417
Mtu-H37Rv DnaB CLTASTRILRADT 13 GREVEATGSHPFMK 77 HVFDGTV**SGTHNFV 408 NGISLHNS 417
Mtu-H37Rv RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-Haarlem DnaB CLTASTRILRADT 13 GREVEATGSHPFMK 77 HVFDGTV**SGTHNFV 408 NGISLHNS 417
Mtu-K85 RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-R604 RecA-n CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77
Mtu-So93 RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-T17 RecA-c RTFDLEV**EELHTLV C347 EGVVVHNC C356
Mtu-T17 RecA-n CLAEGTRIFDPVT N13 VAAAKDGTLHARPV N45
Mtu-T46 RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-T85 RecA CLAEGTRIFDPVT 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mtu-T92 RecA VPRRGHSDLRSGH 13 GAIVWATPDHKVLT 77 RTFDLEV**EELHTLV 432 EGVVVHNC 441
Mvan DnaB ALALDTPLPTPTG 13 GTVIVADAEHQWLT 69 PVRCVEV*DNDDHMYL 406 SMIPTHNS 417
Mvan GyrA CLTGDSMVRLPFG 13 GYEVTGTANHPLLC 79 PVYSLRV*DTDDHSFI 413 NGFVSHNT 422
Mxa RAD25 CVKNDSLIFTDRG 13 GYELEATPEHPIRV 77 DVVDLSV**PETHEFV 428 NGVVCHNT 437
Mxe GyrA CITGDALVALPEG 13 GLRVTGTANHPLLC 79 PVYSLRV*DTADHAFI 190 NGFVSHNT 199
Naz-0708 RIR1-1 CLPEDALVHTSKG 13 ATYPRATLNHKQAV 66 QTYDIEV**EEAHCFY 399 DGYLTHNS 408
Naz-0708 RIR1-2 CLDRTALRIFDQG 13 GRILRMTANHRLSI 73 YSYDFAV**EGIDDND 369 GGIKSHNT 382
Nfa DnaB CLPASTRILRADT 13 GREVEATGNHPFLT 77 DVYDGTV**PGTHNFV 417 QSISVHNS 426
Nfa Nfa15250 CFPAGTVVSGPSA 13 GKQLSLTGNHPVLT 46 HVFSLTSS**EGWHTA 308 NSLIVSNC 314
Nfa RIR1 CFPAGTPVDTIDG 13 KEPIRCTPEHPILV 70 QVYNLHV**EGTHTYT 388 RGAVVHNC 410
Nosp-CCY9414 DnaE-n CLSYDTEILTVEY N13 GSTIRATKDHKFMT N76
Npu DnaB CLAGDSLVTLVDS 13 GRKIRATGNHKFLT 77 EVFDLTV**PGLHNFV 421 NNIIVHNS 430
Npu GyrB CFIGDTLIPLADG 13 GEEIICTPDHQFML 76 DVYCLTV**PEYHNFA 313 AGVFVHNC 323
Npu-PCC73102 DnaE-c NVYDIGV**ERDHNFA C27 NGFIASNC C37
Npu-PCC73102 DnaE-n CLSYETEILTVEY N13 GSVIRATSDHRFLT N76
Nsp-JS614 DnaB ALALDTALPTPSG 13 GSRIVADAQHQWLT 69 PVRCVEV*DNTEHLYL 342 SMIPTHNS 353
Nsp-JS614 TOPRIM CLAGETKVLTWDG 13 RKELFATDGHRWFV 71 EVYCAEV**EDGHAFT 303 DNILTGNC 313
Nsp-PCC7120 DnaB CLTGDSLVTLAPG 13 GCKIRATANHKFLT 77 EVFDLTV**PGLHNFI 421 NNIVVHNS 430
Nsp-PCC7120 DnaE-c NVYDIGV**RRDHNFF C27 NGLIASNC C37
Nsp-PCC7120 DnaE-n CLSYDTEVLTVEY N13 GSIIKATKDHKFMT N76
Nsp-PCC7120 RIR1 CLPEDALVHTAKG 13 ATYPRATLNHRQAV 66 QTYDIEV**DEAHCFY 399 DGYLTHNS 408
Oli DnaE-c NVYDIGV**EKDHNFL C27 SGEIASNC C37
Oli DnaE-n CLSYNTEVLTVEY N13 GSVIRATKDHQFMT N76
PP-PhiEL Helicase AMPLSTRVKVPNG 13 GRTADSHPYHLWKT 68 QETCCIALDNDEKLYV 253 DYIVTHNT 263
PP-PhiEL ORF11 QQRNSAKVRIVPK 13 GRATDVGTEHLWTL 79 DCTCIEV*DNSEQLYL 304 DFIVTHNT 314
PP-PhiEL ORF39 AGVLSSKIKIPGG 13 GRYTDVSPDHLWKV 68 ETQCITI*DHPDHLYI 357 DFIVTHNS 367
PP-PhiEL ORF40 MQPLYAKIKVPGG 13 GRYTDAGLDHLWKV 68 EAQCISV*AHPDRLYI 239 DFIVTHNT 249
Pfl Fha BIL CFAAGTMVATPKG 13 SETLEVTPGHPFYV 81 LTYNLTV**DIGHTFY 138 LGTWVHNV 149
Plut RIR1 CVTAETLVATDRG 13 GYRLKLTGDHPVYT 69 PVFDLTE**PENHHFI 362 NGIGVHNC 371
Pma-EXH1 GyrA CVTGDTLINTDRG 13 GYEIEGSFNHPVLT 78 IVYSIRV*KSDCHSFV 407 NGIVNHNT 416
Pma-ExH1 DnaE CLTGDTLITMADG 13 GLEIKATADHKFLT 78 HVYDIEV**EGTHNFI 401 NNIISHNC 410
Pna RIR1 CVTADTRLATQHG 13 GYQIKATAWHEFYT 81 PVYDTTQ**PDGNTVI 366 NGLVTGQC 375
Pnuc DnaB AQPLDAKVKTVDG 13 GREAECCDEHLWRV 68 QAQCVSV*SHPSRTYV 343 DYVVTHNT 353
Posp-JS666 DnaB AQPLDARVRTRTG 13 GRSTECCAEHLWQV 68 LCQCISV*SHPSKLYI 342 QDVVTHNT 352
Posp-JS666 RIR1 CVTADTWVMTTAG 13 GPALRLTADHRVRR 70 DVFDVTV**ADIHAFD 372 NGLYVHNC 381
Pssp-A1-1 Fha CFAAGTLVATPDG 13 SETLLVTPSHPFYV 81 KTFNLTV**DMGHTFY 138 LRTWVHNT 149
Psy Fha CFAAGTMVSTPDG 13 DESLLVTPGHPFYV 81 KTYNLTV**DVGHTFY 138 LKTWVHNT 149
Rbr-D9 GyrB CFTGDTAIKLADG 13 GDVVRCTPDHRFML 80 DTYDITV**DHHHNFL 144 CGVFVHNS 154
Rce RIR1 CVTAETWVGTAEG 13 GLELRATADHPVRR 70 EVFDVRI**PGANAFE 369 NGLVVHNC 378
Rer-SK121 DnaB ALALDTPLATPSG 13 GTVLVADEQHQWLT 69 PVRCVEV*DNADHMYL 267 SMVPTHNS 278
Rma DnaB CLAGDTLITLADG 13 GRSIRATANHRFLT 76 EVFDLTV**PGPHNFV 420 NDIIAHNS 429
Rma-DSM4252 DnaB CLAGDTLITLADG 13 GRSIRATANHRFLT 76 EVFDLTV**PGPHNFV 420 NDIIAHNS 429
Rma-DSM4252 DnaE CVAEGTLIVDART 13 GRTIELTAEHPLLT 74 RVYDLAV**PPFANFV 415 QDIVVHNS 424
Rsp RIR1 CVTAETWVMTDEG 13 GRHLRLTADHLVRK 70 EVFDVQV**PGVNAFD 364 NGFYVHNC 373
SaP-SETP12 dpol CLHRHTQVLTDGG 13 VDGVLMTEDHKILT 62 PVYDLID*VEDGNRFL 287 GFLVAHNC 300
SaP-SETP3 Helicase CLKRGTEVIMFDG 13 GESYTVNESHILSL 68 GVDDYFGF/DGDSRFL 338 FTVTHNTS 349
SaP-SETP3 dpol CLHRHTQVLTDGG 13 VDGVLMTEDHKILT 62 PVYDLID*VEDGNRFL 287 GFLVAHNC 300
SaP-SETP5 dpol CLHRHTQVLTDGG 13 VDGVLMTEDHKILT 62 PVYDLID*VEDGNRFL 287 GFLVAHNC 300
Sare DnaB CLTADTRLIRADT 13 GKHIDATSNHPFLA 78 DVYDATV**LGTHNFI 369 NGIATHNS 377
Sav RecG Helicase AQPLDSLVLAPTG 13 GSSVECDDEHLWIV 68 PAQCISV*GHPSHAYV 329 NFTVTHNT 339
Sel-PC6301 RIR1 CVTADTWVHTGEG 13 GYSLRPTANHRVLK 70 TVYDCTV**PGPARFD 362 NGLVAHNC 371
Sel-PC7942 DnaE-c PVYDLGV**ATVHNFV C27 NGLVASNC C37
Sel-PC7942 DnaE-n CLAADTEVLTVEY N13 GRIIRATADHRFMT N76
Sel-PC7942 RIR1 CVTADTWVHTGEG 13 GYSLRLTANHRVLK 70 TVYDCTV**PGPARFD 362 NGLVAHNC 371
Sel-PCC6301 DnaE-c PVYDLGV**ATVHNFV C27 NGLVASNC C37
Sel-PCC6301 DnaE-n CLAADTEVLTVEY N13 GRIIRATADHRFMT N76
Sep RIR1 CVTGDTELLTEKG 13 GFKIKSTEWHKYYR 83 DVYDTTQ**EDYHSLI 376 NGIVTGNC 385
ShP-Sfv-2a-2457T-n Primase ACPLNEPILLADG 13 GRYVDCAGDHLWEV 69
ShP-Sfv-2a-301-n Primase ACPLNEPILLADG 13 GRYVDCAGDHLWEV 69
ShP-Sfv-5 Primase ACPLNEPILLADG 13 GRYVDCAGDHLWEV 69 ECLCIMV*DHPRHLYV 333 GYVATHNT 343
SoP-SO1 dpol CLHRHTQVLTNGG 13 VDGVLMTEDHKILT 62 PVYDLIDV*EDGNRFL 287 GFLVAHNC 300
Spl DnaX CLTGDALILSDRG 13 QTEIKCTGNHLIRT 66 HVYDIEV**EHNHNFV 130 NGLLVHNC 137
Sru DnaB CLGKGTPVMMYDG 13 GMDYRVNESHILSL 68 VGDYFGFTLDGNGRFL 335 DGTVTHNT 345
Sru PolBc CFDPETEVVTVDG 13 HTDFLVTPNHRFLT 73 VDYDGMIHCLTVADNH 343 KFNWTGQS 359
Sru RIR1 CLTGDQRVVTDRG 13 GVEQKVSARHGMPV 71 TVYCPTT*HTEESVFV 364 QGALTFNC 373
Ssp DnaB CISGDSLISLAST 13 GRTIKATANHRFLT 77 EVFDLTV**PGPHNFV 421 NDIIVHNS 430
Ssp DnaE-c RIFDIGL**PQDHNFL C27 NGAIAANC C37
Ssp DnaE-n CLSFGTEILTVEY N13 GSVIRATSDHRFLT N76
Ssp DnaX CLTGDSQVLTRNG 13 NSTVRCTANHLIRT 73 KVYDLEV**EDNHNFV 422 NGLLVHNC 431
Ssp GyrB CFSGDTLVALTDG 13 GESIICTPDHKFML 80 DVYDIEV**PHTHNFA 426 SGVFVHNS 436
Ssp-JA2 DnaB CLAGDTQVMDADR 13 NFSIRATGNHPFLT 80 PVYDIEM**PRHHNFV 133 NGLLVHNS 142
Ssp-JA2 RIR1 CVTADTWVHTGDG 13 GFSLRLTGNHRVLK 70 PVYDCTV**PGPACFD 361 NGFVVHNC 370
Ssp-JA3 DnaB CLAGDTRVRDVDR 13 NFSIRATGNHPFLT 80 PVYDIEM**PRHHNFV 133 NGLLVHNS 142
Ssp-JA3 RIR1 CVTADTWIHTGDG 13 GFSLRLTGNHRVLK 70 PVYDCTV**PGPSCFD 361 NGLVVHNC 370
Ssp-PCC7002 DnaE-c PTYDIGL**SQDHNFL C27 QGLIAANC C37
Ssp-PCC7002 DnaE-n CLAGGTPVVTVEY N13 GQMIRATPDHRFLT N76
Ssp-PCC7335 RIR1 CLPEDALVHTARG 13 GPVPRATLNHQIAV 66 QTYDIEV**EEAHCFY 401 DGYLTHNS 410
StP-Twort ORF6 CISMDSMILTTEG 13 GIELVNTYNHPLLV 83 PTFDVCM**PKTHSFI 412 NTIVNHNT 421
Susp-NBC371 DnaB intein CLGKGTNVLMYDG 13 GIDYRVNKSHILSL 68 VEYDKV***DDYYGFV 327 DMTVTHNT 345
Taq-Y51MC23 DnaE CLPARAKVVDWRT 13 GRVLEATANHPLFT 79 EVFDLTV**EGTHTFI 417 EDVIVHNS 426
Taq-Y51MC23 RIR1 CFVGSTRIPTEFG 13 GLELTLTPDHLLLT 86 PVYDLTE**PVTHSLI 396 NGIVAHNC 405
Tcu-DSM43183 RecA CMSYGTRVTLADG 13 RAQFAATENHLVRT 83 MRRFDIEV*EGAHNYF 356 DGVMVHNS 365
Tel DnaE-c AVYDIGL**AADHNFV C25 NGAIAANC C36
Tel DnaE-n CLSGETAVMTVEY N13 GSTICATPDHRFMT N76
Ter DnaB-1 CAAYDTLVLQKDG 13 GRFVETTITHPFLT 75 QVYDLTV**PETHNFV 1978 NDICLHNT 1987
Ter DnaB-2 CLTGESLICLADG 13 GKLIRATANHPFFS 76 EVFDLTV**PGLHNFV 169 NEIVVHNS 178
Ter DnaE-1 CLPKGTLIDQPDG 13 GTVIYSGKNHRFLT 72 ECFDLEMEDQSSPYFL 1358 EGVVVHNC 1366
Ter DnaE-2 CLSGSTKVIDAAT 13 NRKVCATDDHLFYT 81 EVFDLTI**PETHNFI 420 NDFIVHNC 429
Ter DnaE-3c NVYDIGV**TKDHNFV C27 NGLIASNC C37
Ter DnaE-3n CLTYETEIMTVEY N13 GTVIRATPEHKFMT N76
Ter GyrB CFAGNQKVILADG 13 NETIICTPDHLFML 80 DVYDIEV**PHTHNFA 235 SGVFVHNS 245
Ter Ndse-1 CFDSKTEILTEAG 13 HRDFCVTPNHWMYV 72 KVYCVNV**TNHVVFV 326 RAAWCGQC 337
Ter Ndse-2 SLTGDQKVLYYIA 13 GKQIKITEDHSLFT 84 YVYDFSV**PNYENFI 420 YNVFAHNT 431
Ter RIR1-1 CLPEGALVHTASG 13 DGYFECTPDHKVAV 67 STYDIEV**ASIHEFV 386 QGILVSNS 395
Ter RIR1-2 CHSGDTLVSTDQG 13 GMQMRCTGDHQHFT 75 VVYDLHV**PLTNSFI 365 NGCLTHNC 374
Ter RIR1-3 CVSGDTLLITRDS 13 GSYLDVTEYHRFFV 68 GLHDTYC**FEEPEFH 312 GNALTGNC 324
Ter RIR1-4 CLDKTALRIFNQG 13 GRKLRMTPNHRMSV 73 YSYDFAI**EGINDND 369 GALKSHNT 382
Ter Snf2 CVLHDTEIYVNGM 13 GSSITITCRHKLFI 93 WVYDFEV**SKYHNFV 461 NNIICHNT 470
Ter ThyX CLSGNTKVRFRYS 13 GKEIRATLEHQFWT 105 ITYDLEV*EHPEHNFI 290 NGLVVHNS 299
Tfus RecA-1 CLTADTYVWTDRG 13 GRQVTVTRNHPLRV 86 PTFDLMV**PRTHSFL 414 NGILSHNT 423
Tfus RecA-2 CMHYDTLVTLADG 13 GAQFTATPNHLIRT 83 RKFDIEV**EGNHNYF 349 DGVMVHNS 358
Tfus Tfu2914 CVDEETEILTTDG 13 THSSLTTPQHRWPV 74 RVWCVRT**PNATWLA 330 TVYFTGNS 342
Thsp-K90 RIR1 CVTADTWIHTSIG 13 GYQLKLTADHRLRR 70 EVFDVSV**PDVHAFD 370 NGLCAHNC 379
Tth-DSM571 RIR1 CVTGDTWVMTTEG 13 GYSIRLTDDHKILK 70 DVYDVQV**PGINSFD 366 NGIIIHNC 375
Tth-HB27 DnaE-1 CLAEGSLVLDAAT 13 GRTLVLTPDHPLLT 74 RTFDLRV**PPFANFV 415 EDLVVHNS 424
Tth-HB27 DnaE-2 CLPARARVVDWCT 13 GRVLEATANHPVYT 79 EVFDLTV**EGTHTFV 415 EDVIVHNS 424
Tth-HB27 RIR1-1 CLHPDTLVHTDRG 13 GLEVQGTLNHKLKV 76 LTLDLSV**EGNHTYL 430 NGLVSHNT 439
Tth-HB27 RIR1-2 CFVGSTRIPTERG 13 GLEVTLTPDHLLLT 86 PVYDLTE**PVTHSLI 399 NGLVAHNC 408
Tth-HB8 DnaE-1 CLAEGSLVLDAAT 13 GRTLVLTPDHPLLT 74 RTFDLRV**PPFANFV 415 EDLVVHNS 424
Tth-HB8 DnaE-2 CLPARARVVDWCT 13 GRVLEATANHPVYT 79 EVFDLTV**EGTHTFV 415 EDVIVHNS 424
Tth-HB8 RIR1-1 CLHPDTLVHTDRG 13 GLEVQGTLNHKLKV 76 ILTLDLS**EGNHTYL 417 NGLVSHNT 439
Tth-HB8 RIR1-2 CFVGSTRIPTERG 13 GLEVTLTPDHLLLT 86 PVYDLTE**PVTHSLI 399 NGLVAHNC 408
Tvu DnaE-c AVYDIGL**AGDHNFL C26 NGAIAANC C36
Tvu DnaE-n CLSGETAVMTVEY N13 GSTICATPDHRFMT N76
Tye RNR-1 CYSSDTQVLTYSG 13 KLDLLVTPNHRMLV 73 KVYCVEV**PNHTLYV 366 KACWCGNS 378
Tye RNR-2 CLSEDTEILTLDG 13 SQSQLISPNHRVVR 73 GIIWSV***NTENETV 303 QVFITGNT 318 |
Archaea |
Intein Block A Block B Block F Block G
Ape APE0745 SLPPWEPIVVRRG 13 GRSIDLTGSHSIYR 92 FVYDLSV**EGDENFF 458 GWILVHNS 449
Cme-boo Pol-II CFYGETKIEIFDG 13 RTVDTNGGMHLRRI 66 RVYCLTVA**EDHTLV 157 NGVFTGQC 166
Fac-Fer1 RIR1 CVTGDTKIFTSEG 13 GFEIKVTGDHKIYS 74 DVYDLV**EPSTHSFV 360 NGIVVHNC 367
Fac-Fer1 SufB (Fac Pps1) CLPEDELISQGDK 13 GNAFRATSEHPVLS 70 EVYDDIV**YNMEVET 343 KGFAVHNC 357
Fac-TypeI RIR1 CVTGDTKIFTSEG 13 GFEIKVTGDHKIYS 74 DVYDLV**EPSTHSFV 360 NGIVVHNC 367
Fac-typeI SufB (Fac Pps1) CLPEDELISQGDK 13 GNAFRATSEHPVLS 70 EVYDDIV**YNMEVET 343 KGFAVHNC 357
Hma CDC21 CVHGDTRVTLADG 13 GRELDVTPSHPLFV 91 WVYDLEI**EGTHNYL 469 NGVVSHNS 478
Hma Pol-II CFHPDTRLWYEDE 13 DRTLRVTPDHTMLR 96 HVYCLTV**ADTHRVA 172 EGTYVGQC 181
Hma PolB CFTPDTDVLTPEG 13 KMDFRVTPNHRMLV 74 GVYCVTV**ADNHTLM 397 KFQFVGQS 410
Hma TopA CLTADSDVLVRSE 13 RGAVTVTDDHPMYI 98 PVYDLTV*SENAPNFA 528 GGAVVHNS 538
Hmu-DSM12286 MCM CLSGDTHVTLGDG 13 GRELDITPSHPLFV 91 WVYDLEV**GGTHNYV 166 NGVVSHNS 175
Hmu-DSM12286 PolB CFTPDTEVVTPEG 13 KIDFRVTPNHRMLV 74 GVHCVTVE**DNHTLL 399 KFQFVGQS 412
Hsa-R1 MCM CVRGDTTVALADG 13 GHRLTVTPSHPLFV 91 WVYDLEV**EGTHSYL 174 DGVVSHNS 183
Hsp-NRC1 CDC21 CVRGDTTVALADG 13 GHRLTVTPSHPLFV 91 WVYDLEV**EGTHSYL 174 DGVVSHNS 183
Hsp-NRC1 Pol-II CFHPETNVWFRDE 13 GRELTVTPDHSMRR 100 HTYSLTV***AETNTL 186 NGLFTGQC 196
Hut MCM-2 CVTGDTLVQAGDG 13 GEEVTVTPDHPFFI 93 SVYDLTV**EGTHNFL 178 NGMVVHNS 187
Hut-DSM12940 MCM-1 CLDADTNVQLADG 13 GKELDVTPSHPLFV 91 WVYDLEV**EGTHSYV 520 NGVVSHNS 529
Hvo PolB SVTGDRPVVVRDP 13 FGESTTTRDHSYVV 107 YVYDLSV**EENENFV 427 GGIVLHNT 438
Hwa GyrB CFSGDTEIALASG 13 GEVIRCTPDHEFML 80 DVYDLEV**PVTHNFA 206 SGVFVHNS 216
Hwa MCM-1 CVSGETDIALVEG 13 GRSVTVTPSHPVFV 91 WVYDLEV**EGTHAYL 201 NGVLSHNS 210
Hwa MCM-2 CVTGETRIHTTDG 13 GKQLEASVNTPVLT 90 EVFDLTV**PNTQNFI 513 GGIVTHNT 522
Hwa MCM-3 CVTGETLVSLADG 13 GSEVTTTADHPFII 97 DVYDLTV**SGTHNFV 204 NGMIVHNS 212
Hwa MCM-4 SYHPRSEVLLADG 13 GRSVLVTPEHPMFI 97 WVYDITV**EPTNTFI 574 SGVVLHNS 573
Hwa Pol-II-1 CFHPETKIWFRDT 13 GREITITPDHEMHI 102 YTYCLTV**SETHSLI 521 NDLSQKQC 530
Hwa Pol-II-2 SVAADSRLVAVSP 13 GRSLDITDEHSLFR 100 VDYDGYL**YDLQVGG 531 NWLYAHNS 545
Hwa PolB-1 CLPSDARIQMADG 13 GTSLRSSGDHRIMI 71 TTYDIET***TTHNFV 425 DDCLVHNC 435
Hwa PolB-2 CFTPDTNVLTPNG 13 EIDFRVTPNHRMLV 74 GVYCVTV**ADNQTLL 346 TFQWTGNS 359
Hwa PolB-3 SVTGDRPVVVRDP 13 YGESTTTRDHSYIT 108 YVYDLSV**ATNQNFV 421 GGLVLHNT 432
Hwa RCF CVTGSTPILTNKG 13 GATLTVTPEHKLLI 82 RVYDLTV**PGVRNYV 313 IPTVMHNT 324
Hwa RIR1-1 CLTADSTVMLKEK 13 GCSIRGTPNHRLMV 72 TVYDITV**ADNHEYV 400 DGIISHNS 409
Hwa RIR1-2 CVEENSLVSTDEG 13 GFNIAATPNHRFRT 78 YTKDISV**PSNNTYI 430 DGFVTHNT 439
Hwa Top6B SLTPTQTLLIRRD 13 GRTLEITGNHSLFS 95 YVYDISV**PGASGHD 477 GAICVKNS 493
Hwa rPol A'' SIEADESIVIRRD 13 GRSIRATKAHSFVT 100 YVYDLSV**SGLETFT 205 EGVVTHNT 215
Maeo Pol-II CFPPNTTILVNIN 13 GRSFETTPDHPVMV 99 FVYSLNA**KKYHNVV 493 SNIQMHNC 503
Maeo RFC CLTENAKIYTADE 13 GRTIEATEDHKFLT 78 DVYDITC**HNDHSFI 609 NGFVSHNC 618
Maeo RNR SLVKDELIFIKDN 13 GTTVSITEDHSLFN 103 YVYDLSV**EDNENFI 446 TGILCHNT 456
Maeo-N3 Helicase CLNANTEILQESG 13 GLKITTTPNHLFLV 72 YAYDIELPDDGTNDHY 516 NGFIVHNS 525
Maeo-N3 RtcB CLSTDSNILTDDG 13 GRILKGSADHPILL 77 KLYDVSI*LHQSHNFI 477 NGVVVHNC 486
Maeo-N3 UDP GD CFHPDEILFVDFG 13 GREIKITKDHPVVV 86 EVYSVET**DNNLLIS 455 YGLLIHNC 464
Mein-ME PEP CIEGDAKILTDRG 13 KDTIKITPDHKFPI 83 EVYNLTV/DADNEFDHNYI 348 TPIVVFNC 362
Mein-ME RFC SVSKDTPILVKIN 13 GGVLELTGNHSIML 92 FVYDVSV**PNNEMFF 421 IPILLHNS 432
Memar MCM2 CYDDETEVLTESG 13 QVDLAVTPNHRMYV 72 TIYCLEV**PNHTLYV 347 IPVWCGNS 359
Memar Pol-II CFAGDTEITVSDG 13 GRVLTVTPDHAMLV 99 RVYCLTV**AENHTLV 157 NGIFCGQC 166
Mesp-FS406 PolB-1 CHPKGTKVVVKGR 13 VNGLKCTPNHKIPL 64 KVYDLTL**EGRPYYF 351 NGILTHNS 360
Mesp-FS406 PolB-2 SILPDEYLTVIEE 13 GRTIKVTEDHSLFK 100 YVYDLSV**EKYENFL 469 NNIYAHNS 478
Mesp-FS406 PolB-3 SILPNQWMPIVED 13 GREIEVTMGHSLFK 100 YVYDLSV**EDNENFL 480 NNIYAHNS 489
Mesp-FS406-22 LHR CVSPDTKILTNNG 13 GFEIKCTKEHRFLT 72 IKLKKV***YGIINSK 515 NNFISKNS 529
Mfe-AG86 Pol-1 SILPDEYLVVIED 13 GRSIKVTKGHGLFK 100 YVYDLSV**EEDENFL 468 NNIYAHNS 477
Mfe-AG86 Pol-2 SVTENTEIIVKIN 13 TWYVDVTEDHSLIG 92 YVYDIEV**EDTHRFF 378 NGILVHNT 387
Mhu Pol-II CFHGDTLIEIYAD 13 GKNLLVTPDHAMLV 99 RVYCLTV**DRDHNVV 157 NGIFTGQC 166
Mja GF-6P CLHPDTYVILPDG 13 FSELITTGEHKLFV 72 YVYDLEV**EDYHNFI 491 NLIINHNS 500
Mja Helicase CLNANTEILQESG 13 GLEITTTPNHIFLV 72 YAYDIEL*PDDGSNSH 490 NGFIVHNS 502
Mja Hyp-1 CVPPDTLLILENG 13 PEEIILTPEHPVYA 70 FVYNLEV**EDDSSYV 384 VSGTLHNC 393
Mja IF2 CLMPHEKVLTEYG 13 WHSITTTPEHPFLT 90 YVYDLTT***ETHNFI 538 NGIVVHNT 547
Mja KlbA ALAYDEPIYLSDG 13 RREITLTHDHPVYI 101 HIYDLTV**EDNHTYI 157 EGFAVSNC 169
Mja PEP CIEGDAKILTDRG 13 KDTIKITPDHKFPV 83 EVYNITV/NEFNHNYV 399 TPIVVFNC 413
Mja Pol-1 CHPKGTKVVVKGK 13 VNGLKCTPNHKIPL 64 EVYDLTL**EGRPYYF 361 NGILTHNS 370
Mja Pol-2 SILPDEYLTIIEE 13 GRTIKVTRGHSLFK 100 YVYDLSV**EDNENFL 468 NNIYAHNS 477
Mja RFC-1 CLTGDTKVIVNGE 13 GRELKVTTYHPLLI 85 TIYDLHV**PRYHNFI 538 LPTILHNT 549
Mja RFC-2 SVSKDTPILVKID 13 GGYIELTGNHSIMM 91 FVYDVSV**PNNEMFF 426 VPILLHNS 437
Mja RFC-3 CLTGDAKITLPDE 13 GREIEATGDHKFLT 78 DVYDITC**HKDPSFI 535 NGFVSHNC 544
Mja RNR-1 SLGRDELIFIKEG 13 GTSIIVTEDHSLFN 103 YVYDLSV**EDNENFI 444 TGILCHNT 454
Mja RNR-2 SLPYDEKILIFEN 13 GKKVRVTGDHSVFT 101 YVYDISV**EGTENFI 523 GFICLHNT 534
Mja RtcB (Mja Hyp-2) CLTSNSKILTDDG 13 GRVLEGSKDHPVLT 76 KLYDVGI*VSKEHNFI 480 NSIVVHNC 489
Mja TFIIB SVDYNEPIIIKEN 13 NKKVRVTRSHSVFT 97 YAYDLTV**PNAENFV 325 GGFVLHNT 336
Mja UDP GD CFHPDEVLFIDRG 13 GREIKITKDHPVVI 81 YVYSVET**ENSLLIT 446 YGILIHNC 455
Mja r-Gyr CLTPDTYVVLGDG 13 NYELKATPDHCLLV 77 YVYDLSI**KHNQNFI 486 NGVISHNC 495
Mja rPol A' CVDGDTTVLLDGK 13 GREIIATEDHPFYT 78 YVYDITT*ISETHNFI 444 NGFLTGNC 453
Mja rPol A'' SLPYEEKIIIKEG 13 GREITATPYHSFVI 98 YVYDISV**EGLETFT 462 DGVLTHNT 472
Mka CDC48 SIPGDEVVWAKVD 13 GREVIVTEDHSVFT 82 YVYDVV*EVKLGHNFV 385 QGVLLHNS 395
Mka EF2 CVAPETKICLADG 13 GRSIRTTPEHKFLV 96 YVYDFTV**EEHHNFA 514 EGFVVHNT 523
Mka RFC SVSADTPILVRRG 13 DGTIELTGNHAVMV 89 YVYDVSV**PGNEMFF 295 VPVLLHNS 306
Mka RtcB CLAPGTKILTEHG 13 GLTIEGSEDHPVLT 80 RFYDIGV*CHGAHNFI 474 DGVVVHNC 483
Mka VatB CFAPGTRVITASG 13 GAELVVSEDHKFLV 96 YLYDVTVV**PDHTLV 508 NGIITSNC 518
Mth RIR1 CVSGDTIVMTSGG 13 GHCLRLTHDHRVLV 74 DVTDATV**YGASAFT 126 NGFIVHNC 135
Mvu-M7 Helicase CLNAKTEILQENG 13 GLEITTTPNHIFLV 72 YVYDIELPNDGSNDHY 264 NGFVVHNS 275
Mvu-M7 Pol-1 CHPRGTKVIVKNN 13 VNGLKSTPNHKIPV 64 YVYDLTL**EGRPYYF 231 NGILTHNS 240
Mvu-M7 Pol-2 SILPDEYLTVIED 13 GRTIRVTEGHSLFK 97 YVYDLSV**EDNENFL 465 NNIYAHNS 474
Mvu-M7 Pol-3 SVVKDAKVIIKED 13 DRYVDITEDHSIIG 90 YVYDIEV**ENTHRFF 150 NGILVHNT 159
Mvu-M7 UDP GD CFHPDEVLFIDRG 13 GREIKITKDHPVVI 81 YVYSVETENSLLIT 446 YGILIHNC 455
Neq Pol-c ILYDLST**ESGKFYV C23 NGLVLHNT C31
Neq Pol-n SIMDTEIEVIENG N13 INGITLSANHLVLS N83
Nma-ATCC43099 MCM CVTGDTLVHTGDG 13 GEQLTTTADHPFFV 93 RVYDLTV**EGTHNFV 634 NGMVVHNS 643
Nma-ATCC43099 PolB-1 CLPADSDVLMADG 13 GTSLRSSADHRIMV 71 TTYDIE***TTTHNFI 443 EGCLVHNC 452
Nma-ATCC43099 PolB-2 CFTPDTEVLTPDG 13 KIDFRVTPNHRMLV 74 GVYCVTV**EDNHTLL 395 KFQFVGQS 408
Nph CDC21 CVDGDTSVTLASG 13 GRELEVTPSHPLFV 90 WVYDLEV**ESTHSYL 331 NDVVSHNS 340
Nph PolB-1 CFSGDTDVATPDG 13 THDFKVTENHRFLL 74 EDHDGDVHCITAEDNH 386 HLQWVGQS 402
Nph PolB-2 CFTPDTEVLTPDG 13 EIDFRVTPNHRMLV 74 GVYCVTV**EDNHTLL 397 KFQFVGQS 410
Nph rPol A'' SIPADEQVVVRRN 13 GRSIRATKAHSFVT 98 YVYDVSV**EGLETFT 483 DGVVTHNT 493
Pab CDC21-1 CVDYETEVVLGNG 13 GKRIRVTPTHPFFV 98 WVYDLQV**PGYHNFL 156 NGIFVHNS 165
Pab CDC21-2 CVAPETLIITENG 13 GKQITVTPETKLLT 92 HVYDLTV**EGSHSFI 260 NGFVVHNT 269
Pab IF2 CLLPDEKVVVPSV 13 WHGVTVTPEHPFLT 91 YVYDLTT***ETHNFI 386 NGILVHNT 395
Pab KlbA ALYYFSEIQLPNG 13 GKELVLTQDHPVFV 100 YLYDLTV**DINHNYV 188 NGIVVSNC 197
Pab Lon CFSGEETVVIREN 13 DYWFALTPDHKVYT 98 VTYNLTT***EKGNLL 325 NGLFVKNS 334
Pab Moaa CFPPTEEAVFKFG 13 GRTIRTTPEHKFFV 97 YVYDLEV*ENEGHSFV 446 DGILVSNC 456
Pab Pol-II CFPGDTRILVQID 13 GRSFETTVDHPVLV 97 FVFSLNA**KKYHNVI 176 ENIVTHQC 186
Pab RFC-1 CLTGDAKVIANGE 13 GRELKVTPYHPLLV 85 VIYDLHV*PKYHNFIG 490 LPTVLHNT 500
Pab RFC-2 CVTGDTKVYTPDE 13 GRIIEATGDHMFLT 78 DVYDVTC**ARDHSFI 600 NGLVSHNC 609
Pab RIR1-1 CIDGNAKIIFENE 13 GTKILTSPWHPFFV 103 TFYDLTV**DKYQNYL 388 GMIFVHNT 400
Pab RIR1-2 CFTGDTRILTEKG 13 GYELKVTGDHKFLV 71 HVYDLQV**EDVHLLT 430 NGIYTSNS 439
Pab RIR1-3 CVVGETRILTPEG 13 DKQVKYETVHGNAV 69 LVYDFTV**PEHHMYI 374 NGFMSHNC 383
Pab RtcB (Pab Hyp-2) CLAPGSKVLTEHG 13 GRIIEGSEDHPVLT 80 KFYDIGV*YHEAHNFI 428 NGIVVHNC 437
Pab VMA CVDGDTLVLTKEF 13 GRKIKVTPIHKLFT 93 EVYDVTT***ETHNFI 420 MPTLLHNT 430
Par RIR1 CVTGDTRVLTRDG 13 GFEIKATGDHKLLV 103 VVYDFGV**PDYHRYI 384 EGIVSHNC 393
Pfu CDC21 CVAPDSLVVVNDK 13 GKEITVTPETKLLT 94 YVYDLTV**EGSHSFI 359 NGFVVHNT 368
Pfu IF2 CLLPEEKVVLPEI 13 WYSVTVTPEHPFLT 91 YVYDVTT***ETHNFV 379 NGILVHNT 388
Pfu KlbA ALYDFSVIQLSNG 13 GNEIILTRNHPLAF 102 YVYDLTV**EDDHNYV 514 NGILVSNC 523
Pfu Lon CFSGEEVILIEKD 13 DYWLALTPEHKVYT 98 VTYNVTT***ETGNLL 393 NGLFVKNS 402
Pfu RFC CLTGDTKVIANGQ 13 GRELKVTPYHPLLV 85 IIYDLHV**PGYHNFI 515 MPTVVHNT 526
Pfu RIR1-1 CIDGKAKIIFENE 13 GTKILTSPWHPFFV 103 TFYDLTV**ENYQNYL 443 GMIFVHNT 455
Pfu RIR1-2 CVVGDTRILTPEG 13 EEKVEYETVHGRVL 69 IVYDFTV**PNYHMYI 374 NGFMSHNC 383
Pfu RtcB (Pfu Hyp-2) CLAPGTKVLTEHG 13 GTLIEGSEDHPVLT 80 RFYDIGV*YHEAHNFI 473 NGIVVHNC 482
Pfu TopA CLHPDTLILTSQG 13 GTELYLTADHPVLV 72 KVYDLVV**ENYHNFI 365 NGIAVHNC 374
Pfu VMA CVDGDTLILTKEF 13 GRKIKVTPIHKLFT 93 EVYDITT***ETHNFV 415 MPTLLHNT 426
Pho CDC21-1 CVDYDTEVLLGDG 13 GREIRVTPTHPFFT 98 WVYDLQV**PEHHNFI 160 NGIFVHNS 169
Pho CDC21-2 CVAPDTLINTDNG 13 GRSIALTRETKLLT 91 YVYDLTV**EGSHNFV 152 NGFIVHNT 261
Pho IF2 CLLPEERVILPDY 13 WHSVAVTPEHPFLT 91 YVYDVTT***ETHNFI 436 NGILVHNT 445
Pho KlbA ALYDFSIIQLSNG 13 GNEVILTRSHPLFA 101 YVYDLTV**EDDHNYV 512 NGILVSNC 520
Pho LHR CVSGDSKVLTEKG 13 GFEVKCTREHRFLT 71 VYLDVA***YGIINSE 462 NGFVSKNS 476
Pho Lon CFSGEEVIIVEKG 13 DYWLAVTPDHKVFT 98 VTYNVTT***ETGNLL 466 NGLFVKNS 475
Pho Pol I SILPDEWLPIVEN 13 GRRIKITSGHSLFS 100 YVYDLSV**EDNENFL 450 GLLYAHNS 461
Pho Pol-II CFPGDTRILVQIN 13 GSSFETTVDHPVLV 97 FVFSLNA**KKYHTVI 157 ENIVTHQC 167
Pho RFC CLTGDTKVIANGQ 13 GRELKVTPYHPLLV 85 IIYDLHV**PGYHNFI 515 MPTVVHNT 526
Pho RIR1 CVVGDTRILTPEG 13 GYEIIATLDHKIMT 113 IVYDLTV**PGIHSYI 377 NGFISHNC 386
Pho RadA CFARDTEVYYEND 13 GYSLKVTPSHPVLL 97 WVYDLVI**PETHNFI 163 NGLVLHNT 173
Pho RtcB (Pho Hyp-2) CLAPGTRVLTEHG 13 GKVIEGSEDHPVLT 80 KFYDIGV*YHSAHNFI 382 NGIVVHNC 391
Pho VMA CVDGDTLVLTKEF 13 GRKIKVTPIHRLFT 93 EVYDVTT***ETHNFV 366 MPTLLHNT 377
Pho r-Gyr CVTPDTLVSLSDG 13 GHEIKATPDHGLLV 75 KLYDFTT***TTENFI 402 NGIVSHNC 411
Psp-GBD Pol SILPEEWVPLIKN 13 GRKITITEGHSLFV 100 YVYDLSV**DEDENFL 527 GFLYAHNS 538
Pto VMA CVTGDTPVLLADG 13 GREVKVTPVHKLFR 92 DVYDVTT*PDFGSNFV 323 GAILLHNT 334
Smar 1471 SVSYDTPVLIRDP 13 GGKLEATGSHSVFV 91 YVYDISV*PITEAFFG 471 IPILLHNT 481
Smar MCM2 SYHKDFKIMLADG 13 GAEIIVTPEHPVLI 97 WVYDITI**EPYHLFV 342 DGLILHNT 351
Tac-ATCC25905 VMA CVSGDTPVLLDAG 13 GREVRVTPVHKLFV 92 DVYDLMV*PDYGYNFI 163 GLIVLHNT 174
Tac-DSM1728 VMA CVSGDTPVLLDAG 13 GREVRVTPVHKLFV 93 DVYDLMV*PDYGYNFI 164 GLIVLHNT 175
Tag Pol-1 (Tsp-TY Pol-1) CHPADTKVIVKGK 13 INGLKCTPNHKVPV 64 EVYDLTL**EGNPYYF 352 NGILTHNS 361
Tag Pol-2 (Tsp-TY Pol-2) SILPNEWLPIIEN 13 GRKIHITRGHSLFT 100 YVYDLSV**EDNENFL 528 GLLYAHNS 539
Tag Pol-3 (Tsp-TY Pol-3) SVTGDTEIIVKRN 13 SWYIDVTEDHSLIV 92 YVYDIEV**EGTHRFF 149 NGILVHNT 158
Tba Pol-II CFPGDTRILVQLN 13 GRSFETTVDHPVLV 97 WVYSLSVA**KYHTVI 466 DNITTSNC 476
Tfu Pol-1 CHPADTKVIVKGK 13 INGLKCTPNHKLPV 64 KVYDLTL**EGTPYYF 352 NGILTHNS 361
Tfu Pol-2 SVTGDTEVTIRRN 13 SWYLDVTEDHSLIG 92 YVYDIEV**EGTHRFF 381 NGILVHNT 390
Thy Pol-1 SLLPEEWIPLVEN 13 GRRITVTEGHSLFA 100 YVYDLSV**EEDENFL 527 GLLYAHNS 538
Thy Pol-2 SVTGETEIIIKRN 13 SWYLDVTEDHSLIG 92 YVYDIEV**EGTHRFF 381 NGILVHNT 390
Tko CDC21-1 CVAPDSIIKTNLG 13 GLSITVTPETKLLT 85 YVYDLTV**EGSHSFI 132 NGFVVHNT 141
Tko CDC21-2 SYHHDFELLLADG 13 GREITVTPEHPVMV 97 WVYDVTV**EPHHLFV 327 HGLVLHNT 336
Tko Helicase CMHPDTYVVTKSG 13 TVPVKITPEHMVWV 69 DVYNLEV**EGDESYS 396 VGFIVHNS 404
Tko IF2 CLLPDEKVILPEH 13 WHSVSVTPEHPFLT 91 YVYDVTT***ETHNFV 538 NGILVHNT 547
Tko KlbA ALYDFSVIQLSNG 13 GNEVILTKTHPFFV 101 YLYDLTV**DEDHNYV 515 NGILLSNC 524
Tko LHR CVSGDSKILTGKG 13 GFEIKATKEHKFLT 71 AYIDVA***YGIINSE 512 EGFISKNS 526
Tko Pol-1 (Pko Pol-1) CHPADTKVVVKGK 13 INGLKCTPNHKLPV 64 KVYDLTL**EGTPYYF 352 NGILTHNS 361
Tko Pol-2 (Pko Pol-2) SILPEEWLPVLEE 13 GRRIKITSGHSLFS 100 YVYDLSV**EDNENFL 526 GLVYAHNS 537
Tko Pol-II CFPGDTRILVQIN 13 GRSFETTVDHPVLV 97 FVFSLNA**KKYHNVI 465 ESIVTHQC 475
Tko RFC CLTGDAKVIANGR 13 GRELKVTPYHPLLV 85 VIYDLHV**PGYHNFI 530 MPTVVHNT 541
Tko RIR1-1 CIDGNAKIIFEND 13 GTRVLTSPWHPFFV 103 TFYDLTV**ERYQNYL 443 GMVFVHNT 455
Tko RIR1-2 CVVGDTRVLTPEG 13 EEEVKYETVHGKAL 69 IVYDFTV**PEHHSYI 361 NGFMSHNC 383
Tko RadA CFAKDTKVYYEND 13 GYLLRITLLHPVLV 97 WVYDLVI**PETHNFI 473 NGLVLHNT 483
Tko TopA CLHPDSLIPTPQG 13 RTELYLTADHPVLV 72 KVYDLVV**DQYHNFI 503 NGVVVHNC 512
Tko r-Gyr CVTPDTLVSLADG 13 GHEIKATPDHGLLV 75 KLYDFTT***TTENFL 481 NGAVSHNC 490
Tli Pol-1 SILPNEWLPIIEN 13 GRKINITAGHSLFT 100 YVYDLSV**EDNENFL 528 GLLYAHNS 539
Tli Pol-2 SVSGESEIIIRQN 13 SWYIDVTEDHSLIG 92 YVYDIEV**EETHRFF 382 NNILVHNT 391
Tma Pol SLLPEEWIPVVEN 13 GRKITVTKGHSLFA 100 YVYDLSV**EEDENFL 527 GFLYAHNS 538
Ton-NA1 LHR CVPGHSKIFTAEG 13 GFEVEATLGHKFLT 72 VFIKEA***YGILNSE 510 NGFVSKNS 524
Ton-NA1 Pol SILPDEWVPLLID 13 GRKIKVTEGHSLFT 98 YVYDLSV**EENENFL 525 GMIYAHNS 536
Tpe Pol SVTGDSEVIIRRN 13 SWYLDVTEDHSLIG 93 YVYDIEV**EGTHRFF 382 NGILVHNT 391
Tsi-MM739 Lon CFSGKESIIIEKD 13 DYWLTVTPEHKVYT 98 VTYNVTT***ETGNLL 466 NGLFVKNS 475
Tsi-MM739 Pol-1 SILPNEWLPIIEN 13 GRKITVTGGHSLFT 100 YVYDLSV**EGNENFL 528 GLLYAHNS 539
Tsi-MM739 Pol-2 SVTSDTEIIVKRN 13 SWYIDVTEDHSLIV 92 YVYDIEV**EETHRFF 149 NGILVHNT 158
Tsi-MM739 RFC SVSKDTPILVRIN 13 GGKLELTGNHSVMV 92 FVYDVSV**PGNEMFF 426 IPVLLHNS 437
Tsp AM4 RtcB CLAPGSKVLTEHG 13 GKVIEGSEDHPVLT 80 KFYDIGV*YHRAHNFI 473 NGVVVHNC 482
Tsp-AM4 LHR CVPGHSKIITSRG 13 GFEVEATREHKFLT 72 VFIADA***YGILNSK 513 NGFVSKNS 527
Tsp-AM4 Lon CFSGNESVVIREN 13 DYWLALTPDHRVYT 98 VTYNLTT***ERGNLV 466 NGLFVKNS 475
Tsp-AM4 RIR1 CIDGNAKILFENE 13 GTRILTSPWHPFFV 103 TFYDLTV**ENYQNYL 443 GMVFVHNT 455
Tsp-GE8 Pol-1 SILPDEWLPLLVN 13 GRNIKVTEGHSLFA 98 YVYDLSV**EENENFL 525 GMLYAHNS 536
Tsp-GE8 Pol-2 SVAGNTEVIIRRN 13 SWYLDVTEDHSLIG 92 YVYDIEV**EGTHRFF 381 NGILVHNT 390
Tsp-GT Pol-1 SLLPEEWIPLVEN 13 GRRITVTEGHSLFA 100 YVYDLSV**EEDENFL 527 GLLYAHNS 538
Tsp-GT Pol-2 SVTGETEIIIKRN 13 SWYLDVTEDHSLIG 92 YVYDIEV**EGTHRFF 381 NGILVHNT 390
Tsp-OGL-20P Pol SLLPEEWVPVIVG 13 GRRIRVTTGHSLFA 100 YVYDLSV**EEDENFL 527 GLLYAHNS 538
Tthi Pol SLLPEEWVPVIVG 13 GRRIRVTTGHSLFA 100 YVYDLSV**EEDENFL 527 GLLYAHNS 538
Tvo VMA CVSGETPVYLADG 13 GRSVSVTPVHKLFV 95 DVYDLSV*PEYGRNFI 176 GLLVLHNT 187
Tzi Pol SILPDEWIPLLIN 13 GRKIKVTAGHSLFT 98 YVYDLSV**EENENFL 523 GMLYAHNS 533
Unc-ERS PFL CFTGNTEISTDRG 13 SDAISCTLNHEFFV 72 KVYNLEI*DNPTHSYN 436 NLISVSNC 435
Unc-ERS RIR1 CVTADTWVTTAEG 13 GFELRLTADHPVMK 70 KVYDVKI**PGINAFN 299 NGFVVHNC 308
Unc-ERS RNR SLPGDEKILIKSG 13 GKKVRVTAGHNFFC 102 ETYDIAT*DTSTQNFI 580 GFLFVHNT 591
Unc-MetRFS MCM2 SYHPLTEILLADG 13 DREIIVTPEHPVFI 94 YVYDVTV**EPYHCFV 159 QGVILHNS 168 |
CONSENSUS LINE KEY:
h | hydrophobic residues (G,V,L,I,A,M) |
a | acidic residues (D,E) |
r | aromatic residues (F,Y,W) |
p | polar residues (S,T,C) |
/ | to align block, 1 or more AA not shown |
- | motif absent |
. | non-conserved residue |
* | gap introduced into Block F |
underlined residues | conserved in almost all inteins |
capital letters | single letter amino acid code |
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