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Home > Technical Reference > InBase > Hma TopA Intein Hma TopA Intein Intein Name Hma TopA Prototype Allele Extein Name DNA topoisomerase I Intein Class Theoretical Organism Name Haloarcula marismortui ATCC 43049 Organism Description taxon:272569 Domain of Life Archaea Endonuclease Activity Endo Motif DOD Location in Extein K492 Insert Site Comments top-b Intein Size (aa) 537 Intein N-terminal TMEDKGLGTK/C Intein C-terminal HN/STRHNSIEKL Accession No. AAV46558.1 in NCBI/protein Intein aa Sequence >gi|55231139|gb|AAV46558.1|[55231139] Hma TopA intein (including -1 and +1 extein residues) KCLTADSDVLVRSENGDIERQTVDSLFSDGQVVLADGDTDIAVSKETPTVLSLDEATERVSEQESTLVSERPLRDDESVR TIETSRGAVTVTDDHPMYIRQDGEVTVRPASDIEAGTDLVAARRPPDTMVEPSDETVLSWETFAADCDKHSKLYGVDCGT ELAAQRAARDESQTAFAERYGSYGSAVGKYERGEKDVPVWLLGELDIRPDRIHGLNYETSFENPFPLEWSPELAQVIGCL LGDGSIHRNDDENVVDVRYHNTDEALIERFARDIERLFDIEPTVTDRPGRESHHKRKYQVDVPSAVGRVLVCVLEAVTEN GTPGLPDAVRPAFVGALFDDEGHISREGKAFISNTDHTLLTGVGEMLAEMGIETKLAPDQHKLHIRGRRNLEQFLDRIPI ASDEKFYRGLDALDAYDVTTRKAELLEAIRQEPKTSAALAQTLGVTRGSVNKYLRELRESGHIEKQIEGSNRSLDENRTV QYVAADFEGSVYATLRGEPSSVTVEDVERREYDGPVYDLTVSENAPNFAVNGGAVVHNST Block A CLTADSDVLVRSE 13 Block B RGAVTVTDDHPMYI 98 Block C Block D Block E Block H Block F PVYDLTV*SENAPNFA 528 Block G GGAVVHNS 538 Initially Contributed by Fran Perler Contributor's Address Contributor's Phone No. Contributor's FAX No. Contributor's Email address Independently Found By Comments Date Submitted 02/18/2005 References Baliga 2004 Last database update: 11/05/10 InBase Home Background Info Splicing mechanism Splicing motifs DOD Endo motifs Intein registry Intein alleles Selected properties Blast against InBase   Do you have an intein? Submitting data Bibliography Intein links NEB Home