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Tko RFC Intein
Intein Name Tko RFC
Prototype Allele Mja RFC-1
Extein Name Replication factor C
Intein Class Theoretical
Organism Name Thermococcus kodakaraensis KOD1
Organism Description Thermophile, taxon:69014
Domain of Life Archaea
Endonuclease Activity
Endo Motif DOD
Location in Extein K59
Insert Site Comments RFC-a, ATP/GTP-binding site motif A (P-loop)
Intein Size (aa) 540
Intein N-terminal LFAGPPGVGK/C
Intein C-terminal HN/TTAALALARE
Accession No. YP_184631 in NCBI/protein, TK2218
Intein aa Sequence >gi|57642153|ref|YP_184631.1|[57642153] Tko RFC intein (including -1 and +1 extein residues)
KCLTGDAKVIANGRLFELGELVEKVSKGRFGPTPVEGLKVLGIDEDGKLREFEVQYVYKDRAERLIKVRTRLGRELKVTP
YHPLLVNRKNGEIMWVKAEELRPGDRLAVPRFLPAIAEEDPLAEWLGYFIGDGHADSKNKVITFTNTDPSLRQRFMELTE
RLFPDAKIRERIHKNRAPDVYVNSRRAWELVSSLGLAGRKADKVYIPEKGWEGIRSFLRAYFDCDCGVDKNAVVLATASR
EMAEQVTYALAGFGITSKIREKKVRGKTYYHVTISGSENLERFLSEIGFSHREKLERTLKLVKKPNPNLDSLNVNYELIS
YVRDRLKLNFSDDKRSWSHRKARKISWELMKEIYYRLDELERLKESLSRSILIDWNEMAERRKEIAEKTGIRADRLLEYI
KGKRKPSLRNYIKIAKALGIDLEPTINAMRVFARKYSSYAEIGRKLGTWNSSVRIILESNTEKIKELEEIRKIELELIGE
ILSDEKLKEGVAYLIFLSQNELYWDEITEVKELKGDFVIYDLHVPGYHNFIAGNMPTVVHNT
Block A CLTGDAKVIANGR 13
Block B GRELKVTPYHPLLV 85
Block C WLGYFIGDG 132
Block D KVYIPEKG 202
Block E FLRAYFDCDA 225
Block H TASREMAEQVTYALAGFGI 254
Block F VIYDLHV**PGYHNFI 530
Block G MPTVVHNT 541
Initially Contributed by Fran Perler
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Independently Found By
Comments Formly called Pyrococcus kodakaraensis.
Date Submitted 02/28/2005
References Fukui 2005

Last database update: 11/05/10

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