| Intein Name |
Mle-TN SufB (Mle Pps1) |
| Prototype Allele |
|
| Extein Name |
FeS assembly protein SufB, formerly Pps1 |
| Intein Class |
Theoretical |
| Organism Name |
Mycobacterium leprae |
| Organism Description |
Human pathogen, taxon:1769 |
| Domain of Life |
Eubacteria |
| Endonuclease Activity |
|
| Endo Motif |
DOD |
| Location in Extein |
G201 |
| Insert Site Comments |
SufB-a |
| Intein Size (aa) |
386 |
| Intein N-terminal |
ALNTAVWSGG/C |
| Intein C-terminal |
HN/SFIYVPPGVH |
| Accession No. |
CAB16172.1 in NCBI/protein, ML0593, MLCL536 |
| Intein aa Sequence |
>gi|2398707|emb|CAB16172.1| Mle-TN SufB (Mle Pps1) intein (including -1 and +1 extein residues)
GCLTADARINVKGKGLVSIADVQPGDEVFGVNIGCELERGKVLAKVASGTKPVYEMHVAGRALEATGNHQ
FLVARRVEEGKRTRWTAVWAPLEEIESGEPIAVARVLPDDSGTIFFSESELDIKNRTRQCLYFPCQNSVD
LLWLLGLWLGDGHTAAPHKHMRQVAFSVPAGDPVHHTAIRVVSEQFGANVTVVNCGFIVSSKAFETWLAE
LGFSGDEKTKRLPAWIYSLPHEHQLALIGGLVDADGWTESSGATMSIAFASRELLEDVRQLAIGCGLYPD
GALVERTRSATCRDGRIVTSTSWRLRIQGSLDRVGTRTPGKRGKPVSNKGRRQRYVAAAGLNFSSLSTDT
VGFARLKSKTLVGEKPTYDIQVVGLENFVANGIVAHNS |
| Block A |
CLTADARINVKGK 13 |
| Block B |
GRALEATGNHQFLV 72 |
| Block C |
LLGLWLGDG 151 |
| Block D |
TKRLPAWI 225 |
| Block E |
LIGGLVDADG 245 |
| Block H |
FASRELLEDVRQLAIGCGL 276 |
| Block F |
PTYDIQV**VGLENFV 378 |
| Block G |
NGIVAHNS 387 |
| Initially Contributed by |
Shmuel Pietrokovski |
| Contributor's Address |
Molecular Genetics Dept.
Weizmann Institute of Science
P.O. Box 26, Rehovot 76100, Israel
http://bioinfo.weizmann.ac.il/~pietro |
| Contributor's Phone No. |
|
| Contributor's FAX No. |
|
| Contributor's Email address |
Shmuel.Pietrokovski@weizmann.ac.il |
| Independently Found By |
Doug Smith, Genome Therapeutics |
| Comments |
The pps1 extein is referred to as xheA in Smith 1997. A member of the YC24 family of ABC transporters. Identified by Saves as FeS assembly protein SufB (Huet 2005/6). |
| Date Submitted |
|
| References |
Eiglmeier 1993
Pietrokovski 1994
Smith 1997
Huet 2005
Huet 2006 |
