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Mja KlbA Intein
Intein Name Mja KlbA
Prototype Allele Mja KlbA
Extein Name KlbA, kilB operon ORF A
Intein Class Experimental
Organism Name Methanococcus jannaschii (Methanocaldococcus jannaschii DSM 2661)
Organism Description Thermophile, DSM 2661, taxon:2190
Domain of Life Archaea
Endonuclease Activity
Endo Motif None
Location in Extein G404
Insert Site Comments kblA-a
Intein Size (aa) 168
Intein N-terminal LVAMNTGHDG/A
Intein C-terminal SN/CSGTLHANSA
Accession No. Q58191 in NCBI/protein, MJ0781
Intein aa Sequence >gi|2833586|sp|Q58191| Mja Klba intein (including -1 and +1 extein residues)
GALAYDEPIYLSDGNIINIGEFVDKFFKKYKNSIKKEDNGFGWIDIGNENIYIKSFNKLSLIIEDKRILR
VWRKKYSGKLIKITTKNRREITLTHDHPVYISKTGEVLEINAEMVKVGDYIYIPKNNTINLDEVIKVETV
DYNGHIYDLTVEDNHTYIAGKNEGFAVSNC
Block A ALAYDEPIYLSDG 13
Block B RREITLTHDHPVYI 101
Block C None
Block D None
Block E None
Block H None
Block F HIYDLTV**EDNHTYI 157
Block G EGFAVSNC 169
Initially Contributed by Shmuel Pietrokovski
Contributor's Address Molecular Genetics Dept.
Weizmann Institute of Science
P.O. Box 26, Rehovot 76100, Israel
http://bioinfo.weizmann.ac.il/~pietro
Contributor's Phone No.
Contributor's FAX No.
Contributor's Email address Shmuel.Pietrokovski@weizmann.ac.il
Independently Found By J. Dalgaard and S. Mian
Comments The presence of Ala at the intein N-terminus initially suggested that this is an inactive element, but splicing has since been demonstrated (Southworth 2000).
Intein penultimate aa is S, not H.
Putatively identified as a type II secretion system protein (TIGR).
Date Submitted 05/16/1997
References Bult 1996
Dalgaard 1997
Pietrokovski 1998
Southworth 2000

Last database update: 11/05/10

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