| Intein Name |
Mle-TN GyrA |
| Prototype Allele |
Mle-TN GyrA |
| Extein Name |
DNA gyrase subunit A |
| Intein Class |
Experimental |
| Organism Name |
Mycobacterium leprae TN |
| Organism Description |
Human pathogen, STRAIN=TN, taxon:1769 |
| Domain of Life |
Eubacteria |
| Endonuclease Activity |
|
| Endo Motif |
DOD |
| Location in Extein |
Y130 |
| Insert Site Comments |
gyrA-a, After active site Tyr |
| Intein Size (aa) |
420 |
| Intein N-terminal |
GNDPPAAMRY/C |
| Intein C-terminal |
HN/TEARLTPLAM |
| Accession No. |
Q57532 in NCBI/protein, ML0006 |
| Intein aa Sequence |
>gi|2501247|sp|Q57532| Mle-TN GyrA intein (including -1 and +1 extein residues)
YCVSGNSLVRLLFGKSIRIGDIVTGAQFNSDNPIDLKVLDRHGNPVVADYLFHSGEHQTYTVRTTEGYEI
TGTSNHPLLCLVNVGGIPTLLWKLIGEIRSGDYVVLQRIPPVEFGPADWYSTMEALLFGAFISGGFVFQD
HAGFNSLDRDYFTMVVNAYDTVVGGLRCISSRITVSGSTLLELDVYNLIEFKKTRLSGLCGQRSADKLVP
DWLWHSPSTVKRAFLQALFEGEGFSSILSRNIIEISYSTLSERLAADVQQMLLEFGVVSERYCHTVNEYK
VVIANRAQVEMFFTQVGFGVTKQAKLIRDVVSMSPCVGMDINCVPGLATFIRKHCDNRWVEEDSFNQHNV
DCVQHWHHHSAEIVGHIADPDIRAIVTDLTDGRFYYARVASVTDTGIQPVFSLHVDTEDHSFLTNGFISH
NT |
| Block A |
CVSGNSLVRLLFG 13 |
| Block B |
GYEITGTSNHPLLC 79 |
| Block C |
LFGAFISGG 134 |
| Block D |
DKLVPDWL 212 |
| Block E |
FLQALFEGEG 232 |
| Block H |
TLSERLAADVQQMLLEFGV 266 |
| Block F |
PVFSLHV*DTEDHSFL 412 |
| Block G |
NGFISHNT 421 |
| Initially Contributed by |
Stewart Cole |
| Contributor's Address |
Institut Pasteur
Unite de Genetique Moleculaire Bacterienne
28 rue du Dr. Rous
75724 Paris Cedex 15, France |
| Contributor's Phone No. |
|
| Contributor's FAX No. |
|
| Contributor's Email address |
|
| Independently Found By |
|
| Comments |
Partial gyrase extein sequence. |
| Date Submitted |
|
| References |
Eiglmeier 1993
Fsihi 1996
Fsihi 1996B
Smith 1997
Adam 2002 |
