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Pho IF2 Intein
Intein Name Pho IF2
Prototype Allele Mja IF2
Extein Name Translation initiation factor
Intein Class Theoretical
Organism Name Pyrococcus horikoshii OT3
Organism Description Thermophile, taxon:53953
Domain of Life Archaea
Endonuclease Activity
Endo Motif DOD
Location in Extein K22
Insert Site Comments IF2-a, ATP/GTP-binding site motif A (P-loop)
Intein Size (aa) 444
Intein N-terminal AVLGHVDHGK/C
Intein C-terminal HN/TTLLDKIRKT
Accession No. O58822 in NCBI/protein, PH1095
Intein aa Sequence >gi|6016319|sp|O58822| Pho IF2 intein (including -1 and +1 extein residues)
KCLLPEERVILPDYGPITLEELFNMTKETVFKDEEKEVRKLGIRMPVAGVDGRVRLLEGPYVWKVRYKGK
MLRVKLKDWHSVAVTPEHPFLTTRGWVRADQLKPGDYVAVPKILPGKDDKEKFLQYVHEKLKGKVHIKLP
SSDEEWETFFYFAGTIFGRENSVNPEGLTHEVKALLELFKVLFEYPREVLRVLFMAPVRYVANFLRGFFD
INGYVNGEELRVEVRGAPHEVLEELSLILLRLGIVSKIYPTSLAISGRRNLELFRRYIGFSEKQKAKELE
GIIRRSENSESYPIFEELRRIRLLFGFTRAELSSTIPLYSKYESKEAPSYEILMKILNTIEKGSKDLNKK
ITILEGRVRDHEYIEEFKREGLIKDGKLTELGKELLEVWRNREFDSRDVNYLRNIIENFVFLPVEKIEEF
EYDGYVYDVTTETHNFIANGILVHNT
Block A CLLPEERVILPDY 13
Block B WHSVAVTPEHPFLT 91
Block C FAGTIFGRE 159
Block D
Block E FLRGFFDING 212
Block H GAPHEVLEELSLILLRLGI 243
Block F YVYDVTT***ETHNFI 436
Block G NGILVHNT 445
Initially Contributed by Fran Perler
Contributor's Address
Contributor's Phone No.
Contributor's FAX No.
Contributor's Email address
Independently Found By
Comments Intein insertion site numbered using Met1 as listed in above Acc. No.
Motifs by Pietrokovski and Perler.
Date Submitted 07/20/1998
References Kawarabayasi 1998
Kawarabayasi 1998B
Kawarabayasi 2001

Last database update: 11/05/10

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