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Pfu RFC Intein
Intein Name Pfu RFC
Prototype Allele Mja RFC-1
Extein Name Replication factor C
Intein Class Theoretical
Organism Name Pyrococcus furiosus
Organism Description Thermophile, DSM3638, taxon:186497
Domain of Life Archaea
Endonuclease Activity
Endo Motif DOD
Location in Extein K59
Insert Site Comments RFC-a, ATP/GTP-binding site motif A (P-loop)
Intein Size (aa) 525
Intein N-terminal LFAGPPGVGK/C
Intein C-terminal HN/TTAALALARE
Accession No. AAL80216.1 in NCBI/protein, PF0093
Intein aa Sequence >gi|18892003|gb|AAL80216.1|[18892003] Pfu RFC intein (including -1 and +1 extein residues)
KCLTGDTKVIANGQLFELGELVEKLSGGRFGPTPVKGLKVLGIDEDGKLREFEVQYVYKDRTDRlIKI
KTQLGRELKVTPYHPLLVNRENGEIKWIKAEELKPGDKLAIPSFLPLITGENPLAEWLGYFMGSGYAY
PSNSVITFTNEDPLIRQRFMELTEKLFPDAKIRERIHADGTPEVYVVSRKAWSLVNSISLTLIPREGW
KGIRSFLRAYSDCNGRIESDAIVLSTDNNDMAQQIAYALASFGIIAKMDGEDVIISGSDNIERFLNEI
GFSTQSKLKEAQKLIRKTNVRSDGLKINYELISYVKDRLRLNVNDKRNlSYRNAKELSWELMKEIYYR
LEELERLKKVLSEPILIDWNEVAKKSDEVIEKAKIRAEKLLEYIKGERKPSFKEYIEIAKVLGINVER
TIEAMKIFAKRYSSYAEIGRKLGTWNFNVKTILESDTVDNVEILEKIRKIELELIEEILSDGKLKEGI
AYLIFLFQNELYWDEITEVKELRGDFIIYDLHVPGYHNFIAGNMPTVVHNT
Block A CLTGDTKVIANGQ 13
Block B GRELKVTPYHPLLV 85
Block C WLGYFMGSG 132
Block D LTLIPREG 202
Block E FLRAYSDCNG 218
Block H TDNNDMAQQIAYALASFGI 247
Block F IIYDLHV**PGYHNFI 515
Block G MPTVVHNT 526
Initially Contributed by Dennis Maeder
Contributor's Address COMB
701 E.Pratt St.
Baltimore MD 21202
Contributor's Phone No. 410 234-8871
Contributor's FAX No. 410 234-8896
Contributor's Email address maeder@umbi.umd.edu
Independently Found By
Comments
Date Submitted 08/28/1998
References Maeder 1999

Last database update: 11/05/10

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