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Tth-HB27 DnaE-2 Intein
Intein Name Tth-HB27 DnaE-2
Prototype Allele Tth-HB8 DnaE-2
Extein Name DnaE pol subunit, DNA polymerase III alpha subunit
Intein Class Theoretical
Organism Name Thermus thermophilus HB27
Organism Description thermophile, taxon:262724
Domain of Life Eubacteria
Endonuclease Activity
Endo Motif DOD
Location in Extein K1238
Insert Site Comments dnaE-c
Intein Size (aa) 423
Intein N-terminal EAFANYGFNK/C
Intein C-terminal HN/SHAAAYSLLS
Accession No. YP_005775.1 in NCBI/protein, TTC1806
Intein aa Sequence >gi|46200108|ref|YP_005775.1|[46200108] Tth-HB27 DnaE-2 intein (including -1 and +1 extein residues)
KCLPARARVVDWCTGRVVRVGEIVRGEAKGVWVVSLDEARLRLVPRPVVAAFPSGKAQVYALRTATGRVLEATANHPVYT
PEGWRPLGTLAPGDYVALPRHLSYRPSLHLEGHELDLLGFALAEGHLRHPSGVYLYTSSEEELAAMEEALRAFPNTRIRV
VWRRGVAHVYVGRVDRRQEAGAVAFLRRMGLLGLDAKTKRLPEAVFGLPPEEVARFLGRLWTGDGGVDPKGRLIHYATAS
KELAWGVQHLLLRLGLQSRLVEKRFSGGYKGYAVYLLGGLEAARRFAETVGPYLVGKRRQDLEALLASWEKAGRSTGDVL
PLAFLEEVRAAVAEVAQGQVADLLREAGLAEGLLCLGRGRRGLSRATVGRLAALTGSLALLRLAEAEVYWDRVEAVEPLG
EEEVFDLTVEGTHTFVAEDVIVHNS
Block A CLPARARVVDWCT 13
Block B GRVLEATANHPVYT 79
Block C
Block D
Block E
Block H
Block F EVFDLTV**EGTHTFV 415
Block G EDVIVHNS 424
Initially Contributed by Fran Perler
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Independently Found By
Comments Homolog of the catalytic alpha subunit of E. coli DNA polymerase III.
Date Submitted 02/22/2005
References Henne 2004

Last database update: 11/05/10

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