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Mle-TN RecA Intein
Intein Name Mle-TN RecA
Prototype Allele Mle-TN RecA
Extein Name RecA
Intein Class Experimental
Organism Name Mycobacterium leprae, strain TN
Organism Description Human pathogen, taxon:1769
Domain of Life Eubacteria
Endonuclease Activity PI-MleI
Endo Motif DOD
Location in Extein G205
Insert Site Comments recA-b, Disordered loop 2 that interacts with DNA
Intein Size (aa) 365
Intein N-terminal LREKIGVMFG/C
Intein C-terminal HN/SPETTTGGKA
Accession No. S37025 in NCBI/protein, ML0987
Intein aa Sequence >gi|480544|pir||S37025 Mle-TN RecA intein (including -1 and +1 extein residues)
GCMNYSTRVTLADGSTEKIGKIVNNKMDVRVLSYDPVTDRIVPRKVVNWFNNGPAEQFLQFTVEKSGSNG
KSQFAATPNHLIRTPGGWTEAGNLIAGDRVLAVEPHMLSDQQFQVVLGSLMGDGNLSPNLCDRNGVRFRL
LGYGCKQVEYLQWKKALMGNIRHTVRENSMGASFIDFTPLPELVELQRAVYLGDGKKFLSEEYLKALTPL
VLAIWYMDDGSFTVGSKRVQERTAGGSGRIEICVDAMTEGTRVRLRDYLCDTHGLDVRLREVGSAGKAVL
VFSTAATAKFQSLIAPYVAPSMEYKLLPQFRGRGSVTPQFVEPTQQLVPARVLDVHVKLSTRSMNRFDIE
VEGNHNYFVDGVMVHNS
Block A CMNYSTRVTLADG 13
Block B KSQFAATPNHLIRT 83
Block C VLGSLMGDG 123
Block D --------
Block E LQRAVYLGDG 194
Block H FSLEEYLKALTPLVLAIWY 215
Block F NRFDIEV**EGNHNYF 357
Block G DGVMVHNS 366
Initially Contributed by Elaine Davis
Contributor's Address National Institute for Medical Research
The Ridgeway, Mill Hill
London NW7 1AA
England
Contributor's Phone No. 44-181 959 3666 x2358
Contributor's FAX No. 44-181 913 8528
Contributor's Email address e-davis@nimr.mrc.ac.uk
Independently Found By
Comments
Date Submitted
References Eiglmeier 1993
Davis 1994
Smith 1997
Dalgaard 1997
Frischkorn 2000
Singh 2009

Last database update: 11/05/10

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