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Mma GyrA Intein
Intein Name Mma GyrA
Prototype Allele Mle-TN GyrA
Extein Name DNA gyrase subunit A
Intein Class Experimental
Organism Name Mycobacterium malmoense
Organism Description taxon:1780
Domain of Life Eubacteria
Endonuclease Activity
Endo Motif DOD
Location in Extein Y?
Insert Site Comments gyrA-a, After active site Tyr
Intein Size (aa) 420
Intein N-terminal GNNPPAAMRY/C
Intein C-terminal HN/TEAR------
Accession No. CAA05167.1 in NCBI/protein, MMAJ2066
Intein aa Sequence >gi|2546990|emb|CAA05167.1| Mma GyrA intein (including -1 and +1 extein residues)
YCCTGDALVRLPFGHSVRIGNFVPAACPNSDNAVNLKVLDRHGDPVVADQLFHSGEHQTYTVRTAEGYEV
TGTSNHPLLCLVDVGGVPTLLWKLIEEIRPDDHVVLQRTPPVEFGPADWHDVMEALLLGAFISEGFVSEV
RAGFNNCDRDYFAMVVGAYDAVVGGRRYVSSRRIASGSTLHELDIQNIKELKEARLGDLCGQRPADKSVP
DWLWHSPAAVKRVFLQALFEGGGSCSALPRNMIQISYSTRSRQLAVDVQQMLLEFGIITRRYRHAVGEHK
VLITNRAQAELFATRVGFGGAKQEKLTKILGSMPPCAGMDSDHVPGLARFIRKHCGSRWVDKDWLNRHNV
DRIQRWRTSGEKILSHIADPDVRAIATDLTDGRFYYAKVASVTEAGVQPVYSLRVDTDEHAFLTNGFVSH
NT
Block A CCTGDALVRLPFG 13
Block B GYEVTGTSNHPLLC 79
Block C LLGAFISEG 134
Block D DKSVPDWL 212
Block E FLQALFEGGG 232
Block H TRSRQLAVDVQQMLLEFGI 266
Block F PVYSLRV*DTDEHAFL 412
Block G NGFVSHNT 421
Initially Contributed by Janos Posfai
Contributor's Address New England Biolabs, Inc.
32 Tozer Road
Beverly, MA 01915, USA
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Independently Found By Amalio Telenti
Div. of Infectious Diseases
Medecine 2
CHUV
1011 Lausanne, Switzerland
Comments Partial gyrase extein sequence.
Date Submitted 10/20/1997
References Sander 1998
Adam 2002

Last database update: 11/05/10

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