| Intein Name |
Cga PRP8 |
| Prototype Allele |
Cne-AD PRP8 |
| Extein Name |
PRP8, pre-mRNA splicing factor |
| Intein Class |
Theoretical |
| Organism Name |
Cryptococcus gattii (aka Cryptococcus bacillisporus) |
| Organism Description |
Yeast, human pathogen |
| Domain of Life |
Eucarya |
| Endonuclease Activity |
|
| Endo Motif |
None |
| Location in Extein |
A? |
| Insert Site Comments |
PRP8-a, same as A1578 in Sce PRP8 |
| Intein Size (aa) |
170 |
| Intein N-terminal |
TWEGLFWEKA/C |
| Intein C-terminal |
HN/SGFEESMKNK |
| Accession No. |
AAR00331.1 in NCBI/protein, |
| Intein aa Sequence |
>gi|37695593|gb|AAR00331.1|CbaPRP8_WM02.98| Cga PRP8 intein (including -1 and +1 extein residues)
ACLQNGTRLLRADGSEILVEDVQEGDQLLGPDGTSRTASKIVRGEERLYRIKADELEDLVCTHNHILSL
YKKRSGSEQDPSPSTDLSSTDSYERVDVTVDDFVRLPQQEQQKYRLFRSTGFKRADQPSTSSLATLLHI
MSIQLEEKPTKWSGFVVVKDSLYLRHDYLVLHNS |
| Block A |
CLQNGTRLLRADG 13 |
| Block B |
LEDLVCTHNHILSL 68 |
| Block C |
None |
| Block D |
None |
| Block E |
None |
| Block H |
None |
| Block F |
PTKWSGFVVDKDSLYL 161 |
| Block G |
DYLVLHNS 171 |
| Initially Contributed by |
Margi Butler |
| Contributor's Address |
Department of Biochemistry
University of Otago
PO Box 56
Dunedin
New Zealand/Aotearoa |
| Contributor's Phone No. |
|
| Contributor's FAX No. |
|
| Contributor's Email address |
margi.butler@stonebow.otago.ac.nz |
| Independently Found By |
|
| Comments |
The organism is also called Cryptococcus neoformans var gattii and Cryptococcus bacillisporus.
This gene also contains an intron. The PRP8 inteins from numerous Cga strains form 4 clades based on DNA sequence. |
| Date Submitted |
04/27/2003 |
| References |
Butler 2005 |
