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Hca PRP8 Intein
Intein Name Hca PRP8
Prototype Allele Cne-AD PRP8
Extein Name PRP8, pre-mRNA splicing factor
Intein Class Experimental
Organism Name Histoplasma capsulatum
(anamorph: Ajellomyces capsulatus)
Organism Description Fungi, human pathogen
Domain of Life Eucarya
Endonuclease Activity
Endo Motif DOD
Location in Extein A?
Insert Site Comments PRP8-a, same as A1578 in Sce PRP
Intein Size (aa) 534
Intein N-terminal TWEGLFWEKA/C
Intein C-terminal HN/SGFEESMKNK
Accession No. from Paul Liu
Intein aa Sequence >Obtained from Paul Liu| Hca PRP8 intein (including -1 and +1 extein residues)
ACLAKGTQLLRYDGTKVGVENVREGDLLLGPDGEPRRAFNIVSGRDRLYRISIDADKEDLVVTPNHILVLHHEKENQKRQ
SELSASATERYDTVEMTAADFAALDPEERRWYRLFRSPGFELGQQNVPIDPYFVGFWLCDGIRASTTIYTSPEEATREFI
INHAAELDLQLASKEYMQHPVRRVARQTILEQRLAVQCTAPQETDGSLLSHILQKAAKSGLASSTRTMSTSRNRQPLSET
SAATSMNILPGFASNSTSVVSPGIDSHEILSLRNSCSQLVQIAEKSGLREECMINPPSSREDLVLDLFDTHIEADEIQGL
DENLTGQKHRLRTGCRAYGDLTVDEEGQILDNIISRPVGTPDIGTLLRALEELGLPTNRTEGHGVENKRIPLMYMKSSRS
IRLALLAGLIDSDGWYCQPQNTFCFGESERISPTLFWDIVTLARSLGLSVSTEQHTMRSPACTAFKPRFVAQISGNVAEV
TCLLARKRGVKSPVSQAHSFTIKGIHLESEMTEWAGFRVDKDQLYLRHDFLVLHNS
Block A CLAKGTQLLRYDG 13
Block B KEDLVVTPNHILVL 69
Block C FVGFWLCDG 140
Block D NKRIPLMY 393
Block E LLAGLIDSDG 413
Block H RISPTLFWDIVTLARSLGL 447
Block F MTEWAGFRVDKDQLYL 525
Block G DFLVLHNS 535
Initially Contributed by Paul Liu
Contributor's Address
Contributor's Phone No.
Contributor's FAX No.
Contributor's Email address Paul.Liu@Dal.Ca
Independently Found By
Comments
Date Submitted 03/23/2005
References Liu 2004
Butler 2005

Last database update: 11/05/10

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