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Mtu SufB (Mtu Pps1) Intein
Intein Name Mtu SufB (Mtu Pps1)
Prototype Allele Mtu SufB
Extein Name FeS assembly protein SufB, formerly Pps1
Intein Class Theoretical
Organism Name Mycobacterium tuberculosis strains H37Rv & CDC1551
Organism Description Human pathogen, taxon:83332
Domain of Life Eubacteria
Endonuclease Activity
Endo Motif DOD
Location in Extein G252
Insert Site Comments SufB-b
Intein Size (aa) 359
Intein N-terminal EGSYVHYVEG/C
Intein C-terminal HN/CTAPIYKSDS
Accession No. O53152 (Rv1461) & AAK45772.1 (MT1508) in NCBI/protein
Intein aa Sequence >gi|6686194|sp|O53152|for H37Rv|AAK45772.1 for CDC1551| Mtu SufB (Mtu Pps1) intein (including -1 and +1 extein residues)
GCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGELFTFTPMSPANAFSVTAEHPL
LAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKDVAEGDFLIYPKPKPIPHRTVLPLEFARLAGY
YLAEGHACLTNGCESLIFSFHSDEFEYVEDVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDN
VGIGSSNKKLSDLLMRQDETFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYAT
VELRRPGGPGVIMGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPDS
YLAYGFAVHNC
Block A CLPAGELITTADG 13
Block B ANAFSVTAEHPLLA 71
Block C LAGYYLAEG 144
Block D NKKLSDLL 223
Block E LVDAYVNGDG 243
Block H TTSRLWAFQLQSILARLGH 276
Block F PVYNLDV**ENPDSYL 351
Block G YGFAVHNC 360
Initially Contributed by Fran Perler
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Independently Found By
Comments The pps1 extein is referred to as xheA in Smith 1997.
The intein amino acid sequence is identical in both Mtu strains, H37Rv & CDC1551. A member of the YC24 family of ABC transporters. Identified by Saves as FeS assembly protein SufB (Huet 2005/6).
Date Submitted 07/16/1998
References Cole 1998
Saves 2002
Saves 2000
Saves 2002C
Fleischmann 2002
Fleischmann 2004
Huet 2005
Huet 2006

Last database update: 11/05/10

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