| Intein Name |
Mtu SufB (Mtu Pps1) |
| Prototype Allele |
Mtu SufB |
| Extein Name |
FeS assembly protein SufB, formerly Pps1 |
| Intein Class |
Theoretical |
| Organism Name |
Mycobacterium tuberculosis strains H37Rv & CDC1551 |
| Organism Description |
Human pathogen, taxon:83332 |
| Domain of Life |
Eubacteria |
| Endonuclease Activity |
|
| Endo Motif |
DOD |
| Location in Extein |
G252 |
| Insert Site Comments |
SufB-b |
| Intein Size (aa) |
359 |
| Intein N-terminal |
EGSYVHYVEG/C |
| Intein C-terminal |
HN/CTAPIYKSDS |
| Accession No. |
O53152 (Rv1461) & AAK45772.1 (MT1508) in NCBI/protein |
| Intein aa Sequence |
>gi|6686194|sp|O53152|for H37Rv|AAK45772.1 for CDC1551| Mtu SufB (Mtu Pps1) intein (including -1 and +1 extein residues)
GCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGELFTFTPMSPANAFSVTAEHPL
LAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKDVAEGDFLIYPKPKPIPHRTVLPLEFARLAGY
YLAEGHACLTNGCESLIFSFHSDEFEYVEDVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDN
VGIGSSNKKLSDLLMRQDETFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYAT
VELRRPGGPGVIMGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPDS
YLAYGFAVHNC |
| Block A |
CLPAGELITTADG 13 |
| Block B |
ANAFSVTAEHPLLA 71 |
| Block C |
LAGYYLAEG 144 |
| Block D |
NKKLSDLL 223 |
| Block E |
LVDAYVNGDG 243 |
| Block H |
TTSRLWAFQLQSILARLGH 276 |
| Block F |
PVYNLDV**ENPDSYL 351 |
| Block G |
YGFAVHNC 360 |
| Initially Contributed by |
Fran Perler |
| Contributor's Address |
|
| Contributor's Phone No. |
|
| Contributor's FAX No. |
|
| Contributor's Email address |
|
| Independently Found By |
|
| Comments |
The pps1 extein is referred to as xheA in Smith 1997.
The intein amino acid sequence is identical in both Mtu strains, H37Rv & CDC1551. A member of the YC24 family of ABC transporters. Identified by Saves as FeS assembly protein SufB (Huet 2005/6). |
| Date Submitted |
07/16/1998 |
| References |
Cole 1998
Saves 2002
Saves 2000
Saves 2002C
Fleischmann 2002
Fleischmann 2004
Huet 2005
Huet 2006 |
